RIC1

RIC1 homolog, RAB6A GEF complex partner 1
OMIM: 610354, Gene2Phenotype

3 panels

Panel Reviews Mode of inheritance Details
3 panels
Amber RIC1 in Bilateral congenital or childhood onset cataracts


Level 2: Ophthalmology
Version 8.13
Latest signed off version: v8.5 (12 Aug 2026)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Amber
  • Literature
Phenotypes
  • CATIFA syndrome, OMIM:618761
  • Catifa syndrome, MONDO:0032901
Tags
  • watchlist
  • founder-effect
Amber RIC1 in Clefting


Level 2: Musculoskeletal
Version 7.10
Latest signed off version: v7.8 (12 Aug 2026)

Component of the following Super Panels:

  • Paediatric disorders
  • review BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
    Sources
    • Expert Review Amber
    • Literature
    Phenotypes
    • CATIFA syndrome, OMIM:618761
    • Catifa syndrome, MONDO:0032901
    Tags
    • watchlist
    • founder-effect
    Amber RIC1 in Intellectual disability


    Level 2: Developmental disorders
    Version 11.28
    Latest signed off version: v11.0 (12 Aug 2026)

    Component of the following Super Panels:

  • Hypotonic infant
  • Leukodystrophy, childhood onset
  • Paediatric disorders
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Amber
    • Expert list
    Phenotypes
    • CATIFA syndrome, OMIM:618761
    • Catifa syndrome, MONDO:0032901
    Tags
    • watchlist
    • founder-effect