SEM1

SEM1, 26S proteasome complex subunit
OMIM: 601285, Gene2Phenotype

2 panels

Panel Reviews Mode of inheritance Details
2 panels
Red SEM1 in Limb disorders


Level 2: Musculoskeletal
Version 7.20
Latest signed off version: v7.0 (30 Apr 2025)

Component of the following Super Panels:

  • Paediatric disorders
  • review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • Expert Review Red
    • London South East RGC GSTT
    • Viapath
    Phenotypes
    • Split hand/foot malformation 1, 183600
    Tags
    • polygenic
    Red SEM1 in Skeletal dysplasia


    Level 2: Musculoskeletal
    Version 8.34
    Latest signed off version: v8.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Paediatric disorders
  • review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Red
    Phenotypes
    • SHFM1