SPRY4

sprouty RTK signaling antagonist 4
OMIM: 607984, Gene2Phenotype

4 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 4 panels
Amber SPRY4 in Hypogonadotropic hypogonadism Level 3: Hypothalamic and pituitary disorders Level 2: Endocrine disorders Version 1.42	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Amber Literature Radboud University Medical Center, Nijmegen Expert list Phenotypes Hypogonadotropic hypogonadism 17 with or without anosmia, OMIM:615266 Tags monogenic-polygenic
Amber SPRY4 in Hypogonadotropic hypogonadism (GMS) Level 2: Endocrinology Version 4.7 Latest signed off version: v4.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Literature Expert list Radboud University Medical Center, Nijmegen Expert Review Amber Phenotypes Hypogonadotropic hypogonadism 17 with or without anosmia, OMIM:615266 Tags monogenic-polygenic
Red SPRY4 in Fetal anomalies Level 2: Fetal (including NIPD) Version 6.140 Latest signed off version: v6.0 (30 Apr 2025)	review	Unknown	Sources Expert Review Red PAGE Additional Gene List Phenotypes Hypogonadotropic hypogonadism 17 with or without anosmia 615266
Red SPRY4 in Rare syndromic craniosynostosis or isolated multisuture synostosis Level 2: Musculoskeletal Version 6.3 Latest signed off version: v6.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Literature Phenotypes craniosynostosis, MONDO:0015469