TCF3

transcription factor 3
OMIM: 147141, Gene2Phenotype

4 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 4 panels
Green TCF3 in COVID-19 research Level 2: Viral research Version 1.142	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources IUIS Classification December 2031 IUIS Classification February 2018 A- or hypo-gammaglobulinaemia v1.25 London North GLH NHS GMS Victorian Clinical Genetics Services North West GLH ESID Registry 20171117 Expert Review Green NHS GMS North West GLH London North GLH Expert Review Green IUIS Classification February 2018 Victorian Clinical Genetics Services ESID Registry 20171117 A- or hypo-gammaglobulinaemia v1.25 Phenotypes Agammaglobulinemia 8A, autosomal dominant, OMIM:616941 Agammaglobulinemia 8B, autosomal recessive, OMIM:619824 Recurrent bacterial infections Predominantly Antibody Deficiencies
Green TCF3 in Primary immunodeficiency or monogenic inflammatory bowel disease Version 4.202 Latest signed off version: v4.0 (22 Mar 2023)	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources NHS GMS North West GLH London North GLH Expert Review Green IUIS Classification February 2018 Victorian Clinical Genetics Services ESID Registry 20171117 A- or hypo-gammaglobulinaemia v1.25 Phenotypes Agammaglobulinemia 8A, autosomal dominant, OMIM:616941 Agammaglobulinemia 8B, autosomal recessive, OMIM:619824 Recurrent bacterial infections Predominantly Antibody Deficiencies
No list TCF3 in Haematological malignancies cancer susceptibility Level 3: Pertinent cancer susceptibility gene panel Level 2: Cancer Programme Version 4.4 Latest signed off version: v4.0 (22 Mar 2023)	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Literature Phenotypes B-cell acute lymphoblastic leukemia
Green TCF3 in Severe Paediatric Disorders Version 1.184	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Next Generation Children Project Expert Review Green Expert list Phenotypes Agammaglobulinemia 8, autosomal dominant, 616941