GT/TP identifiers for the NHSE Digital Genomic Test Service are temporarily visible in PanelApp but are not yet in use in Genomics England systems

TCP1

t-complex 1
OMIM: 186980, Gene2Phenotype

5 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 5 panels
Amber TCP1 in Malformations of cortical development Level 2: Neurology Version 8.7 Latest signed off version: v8.6 (12 Aug 2026) Component of the following Super Panels: Cerebral malformation Paediatric disorders	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Amber Literature Phenotypes Intellectual developmental disorder with polymicrogyria and seizures, OMIM:621021 intellectual developmental disorder with polymicrogyria and seizures, MONDO:0976124 Tags Q1_26_promote_green
Green TCP1 in Fetal anomalies Level 2: Fetal (including NIPD) Version 8.4 Latest signed off version: v8.0 (12 Aug 2026)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources NHS GMS Expert Review Green Phenotypes Intellectual developmental disorder with polymicrogyria and seizures, OMIM:621021
Green TCP1 in DDG2P Version 8.1 Latest signed off version: v8.0 (12 Aug 2026) Component of the following Super Panels: Paediatric disorders	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources DD-Gene2Phenotype Expert Review Green Phenotypes TCP1-related neurodevelopmental disorder with polymicrogyria Tags de novo
Amber TCP1 in Early onset or syndromic epilepsy Level 2: Neurology Version 9.72 Latest signed off version: v9.56 (12 Aug 2026) Component of the following Super Panels: Paediatric disorders Unexplained death in infancy and sudden unexplained death in childhood	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Amber Literature Phenotypes Intellectual developmental disorder with polymicrogyria and seizures, OMIM:621021 intellectual developmental disorder with polymicrogyria and seizures, MONDO:0976124 Tags Q1_26_promote_green
Amber TCP1 in Intellectual disability Level 2: Developmental disorders Version 11.17 Latest signed off version: v11.0 (12 Aug 2026) Component of the following Super Panels: Hypotonic infant Leukodystrophy, childhood onset Paediatric disorders	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Amber Literature Phenotypes Intellectual developmental disorder with polymicrogyria and seizures, OMIM:621021 intellectual developmental disorder with polymicrogyria and seizures, MONDO:0976124 Tags Q1_26_promote_green