1. Genes and Genomic Entities
  2. TENM3

TENM3

teneurin transmembrane protein 3
OMIM: 610083, Gene2Phenotype

5 panels

Panel Reviews Mode of inheritance Details
5 panels
Green TENM3 in Ocular coloboma

Level 3: Ocular malformations
Level 2: Ophthalmological disorders
Version 1.51

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Literature
  • Radboud University Medical Center, Nijmegen
Phenotypes
  • Microphthalmia, syndromic 15, OMIM:615145
  • ?Microphthalmia, isolated, with coloboma 9, OMIM:615145
  • Microphthalmia, isolated, with coloboma 9, MONDO:0014059
Green TENM3 in Fetal anomalies


Level 2: Fetal (including NIPD)
Version 6.157
Latest signed off version: v6.0 (30 Apr 2025)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Literature
Phenotypes
  • Microphthalmia, syndromic 15, OMIM:615145
  • ?Microphthalmia, isolated, with coloboma 9, OMIM:615145
  • Microphthalmia, isolated, with coloboma 9, MONDO:0014059
Green TENM3 in Anophthalmia or microphthalmia

Level 3: Ocular malformations
Level 2: Ophthalmological disorders
Version 1.56

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Radboud University Medical Center, Nijmegen
Phenotypes
  • Microphthalmia, syndromic 15, OMIM:615145
  • ?Microphthalmia, isolated, with coloboma 9, OMIM:615145
  • Microphthalmia, isolated, with coloboma 9, MONDO:0014059
Green TENM3 in Intellectual disability


Level 2: Developmental disorders
Version 9.304
Latest signed off version: v9.0 (30 Apr 2025)

Component of the following Super Panels:

  • Childhood onset leukodystrophy
  • Hypotonic infant
  • Paediatric disorders

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Expert list
    Phenotypes
    • Microphthalmia, syndromic 15, OMIM:615145
    • ?Microphthalmia, isolated, with coloboma 9, OMIM:615145
    • Microphthalmia, isolated, with coloboma 9, MONDO:0014059
    Green TENM3 in Structural eye disease


    Level 2: Ophthalmology
    Version 4.40
    Latest signed off version: v4.0 (7 Aug 2024)

    		review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • NHS GMS
    Phenotypes
    • Microphthalmia, syndromic 15, OMIM:615145
    • ?Microphthalmia, isolated, with coloboma 9, OMIM:615145
    • Microphthalmia, isolated, with coloboma 9, MONDO:0014059