TIRAP

TIR domain containing adaptor protein
OMIM: 606252, Gene2Phenotype

2 panels

Panel	Reviews	Mode of inheritance	Details
Green TIRAP in COVID-19 research Level 2: Viral research Version 1.147	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green IUIS Classification December 2019 IUIS Classification February 2018 ESID Registry 20171117 IUIS Classification December 2019 IUIS Classification February 2018 ESID Registry 20171117 Phenotypes Staphylococcal disease during childhood Defects of TLR/NFkappa-B signalling TIRAP deficiency Defects in intrinsic and innate immunity Defects in Intrinsic and Innate Immunity
Red TIRAP in Primary immunodeficiency or monogenic inflammatory bowel disease Level 2: Immunology Version 8.85 Latest signed off version: v8.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources IUIS Classification December 2019 IUIS Classification February 2018 Expert Review Red ESID Registry 20171117 Phenotypes Defects in Intrinsic and Innate Immunity Staphylococcal disease during childhood Defects of TLR/NFkappa-B signalling TIRAP deficiency Defects in intrinsic and innate immunity

Panel

Reviews

Mode of inheritance

Details

Level 2: Viral research
Version 1.147

review

BIALLELIC, autosomal or pseudoautosomal

Level 2: Immunology
Version 8.85
Latest signed off version: v8.0 (30 Apr 2025)

review

BIALLELIC, autosomal or pseudoautosomal