1. Genes and Genomic Entities
  2. TIRAP

TIRAP

TIR domain containing adaptor protein
OMIM: 606252, Gene2Phenotype

2 panels

Panel Reviews Mode of inheritance Details
2 panels
Green TIRAP in COVID-19 research


Level 2: Viral research
Version 1.141

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • IUIS Classification December 2019
  • IUIS Classification February 2018
  • ESID Registry 20171117
  • IUIS Classification December 2019
  • IUIS Classification February 2018
  • ESID Registry 20171117
Phenotypes
  • Staphylococcal disease during childhood
  • Defects of TLR/NFkappa-B signalling
  • TIRAP deficiency
  • Defects in intrinsic and innate immunity
  • Defects in Intrinsic and Innate Immunity
Red TIRAP in Primary immunodeficiency or monogenic inflammatory bowel disease


Version 4.201
Latest signed off version: v4.0 (22 Mar 2023)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • IUIS Classification December 2019
  • IUIS Classification February 2018
  • Expert Review Red
  • ESID Registry 20171117
Phenotypes
  • Defects in Intrinsic and Innate Immunity
  • Staphylococcal disease during childhood
  • Defects of TLR/NFkappa-B signalling
  • TIRAP deficiency
  • Defects in intrinsic and innate immunity