TNFSF11

TNF superfamily member 11
OMIM: 602642, Gene2Phenotype

5 panels

Panel Reviews Mode of inheritance Details
5 panels
Green TNFSF11 in COVID-19 research


Level 2: Viral research
Version 1.147

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • IUIS Classification December 2019
  • IUIS Classification February 2018
  • IUIS Classification December 2019
  • IUIS Classification February 2018
Phenotypes
  • Osteopetrosis with severe growth retardation
  • Defects in intrinsic and innate immunity
  • Defects in Intrinsic and Innate Immunity
Red TNFSF11 in Primary immunodeficiency or monogenic inflammatory bowel disease


Level 2: Immunology
Version 9.92
Latest signed off version: v9.91 (12 Aug 2026)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • IUIS Classification December 2019
  • IUIS Classification February 2018
Phenotypes
  • Defects in Intrinsic and Innate Immunity
  • Osteopetrosis with severe growth retardation
  • Defects in intrinsic and innate immunity
Green TNFSF11 in Skeletal dysplasia


Level 2: Musculoskeletal
Version 10.1
Latest signed off version: v10.0 (12 Aug 2026)

Component of the following Super Panels:

  • Paediatric disorders
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • NHS GMS
    • Expert Review Green
    • UKGTN
    • Illumina TruGenome Clinical Sequencing Services
    • Emory Genetics Laboratory
    • Radboud University Medical Center, Nijmegen
    • Expert list
    Phenotypes
    • Osteopetrosis, autosomal recessive 2 259710
    Red TNFSF11 in Fetal anomalies


    Level 2: Fetal (including NIPD)
    Version 8.1
    Latest signed off version: v8.0 (12 Aug 2026)

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Red
    • NHS GMS
    Phenotypes
    • Osteopetrosis, autosomal recessive 2, OMIM:259710
    Green TNFSF11 in Osteopetrosis


    Level 2: Musculoskeletal
    Version 2.3
    Latest signed off version: v2.2 (12 Aug 2026)

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • NHS GMS
    • Expert Review Green
    Phenotypes
    • Osteopetrosis, autosomal recessive 2 OMIM:259710