1. Genes and Genomic Entities
  2. TNFSF12

TNFSF12

TNF superfamily member 12
OMIM: 602695, Gene2Phenotype

2 panels

Panel Reviews Mode of inheritance Details
2 panels
Green TNFSF12 in COVID-19 research


Level 2: Viral research
Version 1.146

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
  • IUIS Classification February 2018
  • IUIS Classification December 2019
  • GRID V2.0
  • Victorian Clinical Genetics Services
  • ESID Registry 20171117
  • IUIS Classification December 2019
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • ESID Registry 20171117
  • GRID V2.0
Phenotypes
  • Immunodeficiency, common variable with lack of anti-pneumococcal antibody
  • Common variable immunodeficiency disorders (CVID)
  • Predominantly Antibody Deficiencies
  • Pneumonia, bacterial infections, warts, thrombocytopenia
  • Pneumonia, bacterial infections, warts, thrombocytopenia. neutropenia
Red TNFSF12 in Primary immunodeficiency or monogenic inflammatory bowel disease


Level 2: Immunology
Version 8.78
Latest signed off version: v8.0 (30 Apr 2025)

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • IUIS Classification December 2019
  • Expert Review Red
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • ESID Registry 20171117
  • GRID V2.0
Phenotypes
  • Common variable immunodeficiency disorders (CVID)
  • Immunodeficiency, common variable with lack of anti-pneumococcal antibody
  • Pneumonia, bacterial infections, warts, thrombocytopenia. neutropenia
  • Predominantly Antibody Deficiencies
  • Pneumonia, bacterial infections, warts, thrombocytopenia