TP73

tumor protein p73
OMIM: 601990, Gene2Phenotype

5 panels

Panel Reviews Mode of inheritance Details
5 panels
Green TP73 in Malformations of cortical development


Level 2: Neurology
Version 7.39
Latest signed off version: v7.0 (30 Oct 2024)

Component of the following Super Panels:

  • Cerebral malformation
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • NHS GMS
    • Expert Review Green
    • Expert list
    Phenotypes
    • Ciliary dyskinesia, primary, 47, and lissencephaly, OMIM:619466
    Green TP73 in Respiratory ciliopathies including non-CF bronchiectasis


    Level 2: Respiratory
    Version 4.55
    Latest signed off version: v4.0 (30 Apr 2025)

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • NHS GMS
    • Literature
    Phenotypes
    • Ciliary dyskinesia, primary, 47, and lissencephaly, OMIM:619466
    Green TP73 in Fetal anomalies


    Level 2: Fetal (including NIPD)
    Version 6.163
    Latest signed off version: v6.0 (30 Apr 2025)

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • NHS GMS
    Phenotypes
    • Ciliary dyskinesia, primary, 47, and lissencephaly, OMIM:619466
    Green TP73 in DDG2P


    Version 6.432
    Latest signed off version: v6.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Paediatric disorders
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • DD-Gene2Phenotype
    • Expert Review Green
    Phenotypes
    • TP73-related ciliary dyskinesia and lissencephaly, OMIM:619466
    Green TP73 in Intellectual disability


    Level 2: Developmental disorders
    Version 9.327
    Latest signed off version: v9.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Childhood onset leukodystrophy
  • Hypotonic infant
  • Paediatric disorders
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Expert list
    Phenotypes
    • Ciliary dyskinesia, primary, 47, and lissencephaly, OMIM:619466