1. Genes and Genomic Entities
  2. TRAF3

TRAF3

TNF receptor associated factor 3
OMIM: 601896, Gene2Phenotype

2 panels

Panel Reviews Mode of inheritance Details
2 panels
Green TRAF3 in COVID-19 research


Level 2: Viral research
Version 1.147

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
  • Melbourne Genomics Health Alliance Immunology Flagship
  • IUIS Classification December 2019
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • ESID Registry 20171117
  • GRID V2.0
Phenotypes
  • Herpetic encephalitis (HSE)
  • Herpes simplex virus 1 encephalitis
  • Defects in Intrinsic and Innate Immunity
  • Defects in intrinsic and innate immunity
  • {?Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 5},614849
  • Herpes simplex encephalitis, susceptibility to, 3
Green TRAF3 in Primary immunodeficiency or monogenic inflammatory bowel disease


Level 2: Immunology
Version 8.88
Latest signed off version: v8.0 (30 Apr 2025)

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • NHS GMS
  • IUIS Classification December 2019
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • ESID Registry 20171117
  • GRID V2.0
Phenotypes
  • {?Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 5}, OMIM:614849
  • immune dysregulation, autoimmunity, and autoinflammation, MONDO:0957790