1. Genes and Genomic Entities
  2. TRIP13

TRIP13

thyroid hormone receptor interactor 13
OMIM: 604507, Gene2Phenotype

8 panels

Panel Reviews Mode of inheritance Details
8 panels
Green TRIP13 in Childhood solid tumours


Level 2: Cancer susceptibility
Version 5.12
Latest signed off version: v5.11 (6 May 2026)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • NHS GMS
  • Expert List
  • Expert Review Green
  • Literature
Phenotypes
  • Mosaic variegated aneuploidy syndrome 3 617598
  • Mosaic variegated aneuploidy syndrome 3 617598
Green TRIP13 in Childhood solid tumours cancer susceptibility

Level 3: Pertinent cancer susceptibility gene panel
Level 2: Cancer Programme
Version 1.30

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
Phenotypes
  • Mosaic variegated aneuploidy syndrome 3 617598
Amber TRIP13 in Severe microcephaly


Level 2: Neurology
Version 9.3
Latest signed off version: v9.0 (6 May 2026)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Amber
  • Literature
Phenotypes
  • Mosaic variegated aneuploidy syndrome 3, OMIM:617598
Tags
  • watchlist
Amber TRIP13 in Fetal anomalies


Level 2: Fetal (including NIPD)
Version 7.7
Latest signed off version: v7.0 (6 May 2026)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Amber
  • PAGE DD-Gene2Phenotype
Phenotypes
  • Mosaic Variegated Aneuploidy and Wilms Tumour
Green TRIP13 in DDG2P


Version 7.1
Latest signed off version: v7.0 (6 May 2026)

Component of the following Super Panels:

  • Paediatric disorders

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • DD-Gene2Phenotype
    Phenotypes
    • Mosaic Variegated Aneuploidy and Wilms Tumour
    Amber TRIP13 in Early onset or syndromic epilepsy


    Level 2: Neurology
    Version 9.7
    Latest signed off version: v9.0 (6 May 2026)

    Component of the following Super Panels:

  • Paediatric disorders
  • Unexplained death in infancy and sudden unexplained death in childhood

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Wessex and West Midlands GLH
    • NHS GMS
    • Expert Review Amber
    • Victorian Clinical Genetics Services
    Phenotypes
    • Mosaic variegated aneuploidy syndrome 3, 617598
    Tags
    • watchlist
    Red TRIP13 in Intellectual disability


    Level 2: Developmental disorders
    Version 10.17
    Latest signed off version: v10.0 (6 May 2026)

    Component of the following Super Panels:

  • Childhood onset leukodystrophy
  • Hypotonic infant
  • Paediatric disorders

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Victorian Clinical Genetics Services
    • Literature
    Phenotypes
    • Mosaic variegated aneuploidy syndrome 3 617598
    Tags
    • watchlist
    Green TRIP13 in Embryonal tumour of possible germline origin


    Level 2: Inherited cancer
    Version 1.1
    Latest signed off version: v1.0 (6 May 2026)

    		review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • NHS GMS
    Phenotypes
    • Mosaic variegated aneuploidy syndrome 3, OMIM:617598
    • mosaic variegated aneuploidy syndrome 3, MONDO:0054736