UNG

uracil DNA glycosylase
OMIM: 191525, Gene2Phenotype

3 panels

Panel Reviews Mode of inheritance Details
3 panels
Green UNG in COVID-19 research


Level 2: Viral research
Version 1.142

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • IUIS Classification February 2018
  • A- or hypo-gammaglobulinaemia v1.25
  • London North GLH
  • GOSH PID v.8.0
  • NHS GMS
  • GRID V2.0
  • Victorian Clinical Genetics Services
  • North West GLH
  • ESID Registry 20171117
  • Expert Review Green
  • NHS GMS
  • North West GLH
  • London North GLH
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • Expert Review Green
  • ESID Registry 20171117
  • GRID V2.0
  • GOSH PID v.8.0
  • A- or hypo-gammaglobulinaemia v1.25
Phenotypes
  • Hyper IgM syndrome with lymphoid hyperplasia
  • Immunodeficiency with hyper IgM, type 5, 608106
  • Enlarged lymph nodes and germinal centers
  • Predominantly Antibody Deficiencies
  • CSR defects and Hyper IgM (HIGM) syndromes
  • Immunodeficiency with hyper IgM, type 5
Green UNG in Primary immunodeficiency or monogenic inflammatory bowel disease


Version 4.202
Latest signed off version: v4.0 (22 Mar 2023)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • NHS GMS
  • North West GLH
  • London North GLH
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • Expert Review Green
  • ESID Registry 20171117
  • GRID V2.0
  • GOSH PID v.8.0
  • A- or hypo-gammaglobulinaemia v1.25
Phenotypes
  • Immunodeficiency with hyper IgM, type 5
  • Hyper IgM syndrome with lymphoid hyperplasia
  • CSR defects and Hyper IgM (HIGM) syndromes
  • Immunodeficiency with hyper IgM, type 5, 608106
  • Enlarged lymph nodes and germinal centers
  • Predominantly Antibody Deficiencies
Green UNG in Severe Paediatric Disorders


Version 1.184

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Next Generation Children Project
  • Expert Review Green
  • Expert list
Phenotypes
  • Immunodeficiency with hyper IgM, type 5, 608106