WIPF1

WAS/WASL interacting protein family member 1
OMIM: 602357, Gene2Phenotype

5 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 5 panels
Green WIPF1 in COVID-19 research Level 2: Viral research Version 1.142	review	BIALLELIC, autosomal or pseudoautosomal	Sources IUIS Classification February 2018 London North GLH NHS GMS GRID V2.0 Victorian Clinical Genetics Services North West GLH ESID Registry 20171117 Expert Review Green NHS GMS North West GLH London North GLH Expert Review Green IUIS Classification February 2018 Victorian Clinical Genetics Services ESID Registry 20171117 GRID V2.0 Phenotypes WIP deficiency ?Wiskott-Aldrich syndrome 2 614493 Wiskott-Aldrich syndrome like, WIP deficiency Combined immunodeficiencies with associated or syndromic features Thrombocytopenia with or without small platelets, recurrent bacterial and viral infections, eczema, bloody diarrhea, WAS protein absent
Green WIPF1 in Primary immunodeficiency or monogenic inflammatory bowel disease Version 4.202 Latest signed off version: v4.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS North West GLH London North GLH Expert Review Green IUIS Classification February 2018 Victorian Clinical Genetics Services ESID Registry 20171117 GRID V2.0 Phenotypes Wiskott-Aldrich syndrome like, WIP deficiency WIP deficiency ?Wiskott-Aldrich syndrome 2 614493 Thrombocytopenia with or without small platelets, recurrent bacterial and viral infections, eczema, bloody diarrhea, WAS protein absent Combined immunodeficiencies with associated or syndromic features
Green WIPF1 in Cytopenias and congenital anaemias Level 3: Anaemias and red cell disorders Level 2: Haematological disorders Version 1.118	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Radboud University Medical Center, Nijmegen Phenotypes Wiskott-Aldrich syndrome like, WIP deficiency WIP deficiency ?Wiskott-Aldrich syndrome 2 614493 Thrombocytopenia with or without small platelets, recurrent bacterial and viral infections, eczema, bloody diarrhea, WAS protein absent
Green WIPF1 in Cytopenia - NOT Fanconi anaemia Version 3.33 Latest signed off version: v3.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green North West GLH NHS GMS Wessex and West Midlands GLH Phenotypes WIP deficiency Wiskott-Aldrich syndrome like, WIP deficiency ?Wiskott-Aldrich syndrome 2, 614493 Thrombocytopenia with or without small platelets, recurrent bacterial and viral infections, eczema, bloody diarrhea, WAS protein absent ?Wiskott-Aldrich syndrome 2, 614493
Amber WIPF1 in Severe Paediatric Disorders Version 1.184	review	BIALLELIC, autosomal or pseudoautosomal	Sources Next Generation Children Project Expert Review Amber Expert list Phenotypes ?Congenital heart defects, hamartomas of tongue, and polysyndactyly, 217085 ?Bardet-Biedl syndrome 15, 615992