1. Genes and Genomic Entities
  2. WNT7A

WNT7A

Wnt family member 7A
OMIM: 601570, Gene2Phenotype

8 panels

Panel Reviews Mode of inheritance Details
8 panels
Green WNT7A in Radial dysplasia

Level 3: Dysmorphic disorders
Level 2: Dysmorphic and congenital abnormality syndromes
Version 1.25

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Expert list
  • Other
Phenotypes
  • Ulna and fibula, absence of, with severe limb deficiency, 276820
  • Short, bowed radii
  • absence of a radius
  • Fuhrmann syndrome, 228930
Red WNT7A in VACTERL-like phenotypes

Level 3: Limb disorders
Level 2: Dysmorphic and congenital abnormality syndromes
Version 1.35

review Not set
Sources
  • Emory Genetics Laboratory
Green WNT7A in Limb disorders


Level 2: Musculoskeletal
Version 7.22
Latest signed off version: v7.0 (30 Apr 2025)

Component of the following Super Panels:

  • Paediatric disorders

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Victorian Clinical Genetics Services
    • Radboud University Medical Center, Nijmegen
    • UKGTN
    • Expert Review Green
    • Emory Genetics Laboratory
    • Expert list
    • London South East RGC GSTT
    • Viapath
    Phenotypes
    • Polydactyly
    • Ulna and fibula, absence of, with severe limb deficiency 276820
    • absence of a radius
    • Fuhrmann syndrome, 228930
    • Fuhrmann syndrome 228930
    • Ulna and fibula, absence of, with severe limb deficiency, 276820
    • Short, bowed radii
    Red WNT7A in Ectodermal dysplasia


    Level 2: Dermatology
    Version 4.25
    Latest signed off version: v4.0 (30 Apr 2025)

    		review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Red
    Phenotypes
    • Fuhrmann syndrome, 228930
    Green WNT7A in Skeletal dysplasia


    Level 2: Musculoskeletal
    Version 8.38
    Latest signed off version: v8.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Paediatric disorders

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • NHS GMS
    • Expert Review Green
    • Emory Genetics Laboratory
    • Expert list
    • Radboud University Medical Center, Nijmegen
    • UKGTN
    Phenotypes
    • Ulna and fibula, absence of, with severe limb deficiency 276820
    • Fuhrmann syndrome 228930
    Green WNT7A in Fetal anomalies


    Level 2: Fetal (including NIPD)
    Version 6.172
    Latest signed off version: v6.0 (30 Apr 2025)

    		review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • PAGE DD-Gene2Phenotype
    • Expert Review Green
    Phenotypes
    • FUHRMANN SYNDROME
    • LIMB/PELVIS-HYPOPLASIA/APLASIA SYNDROME
    Green WNT7A in DDG2P


    Version 6.438
    Latest signed off version: v6.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Paediatric disorders

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • DD-Gene2Phenotype
    • Expert Review Green
    Phenotypes
    • FUHRMANN SYNDROME 228930
    • LIMB/PELVIS-HYPOPLASIA/APLASIA SYNDROME 276820
    Red WNT7A in Intellectual disability


    Level 2: Developmental disorders
    Version 9.331
    Latest signed off version: v9.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Childhood onset leukodystrophy
  • Hypotonic infant
  • Paediatric disorders

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Red
    • BRIDGE study SPEED NEURO Tier1 Gene
    Phenotypes
    • Ulna and fibula, absence of, with severe limb deficiency, 276820
    • Fuhrmann syndrome, 228930