ZFP57

ZFP57 zinc finger protein
OMIM: 612192, Gene2Phenotype

11 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 11 panels
No list ZFP57 in Multi-organ autoimmune diabetes Level 3: Disorders of unusual phenotypes Level 2: Endocrine disorders Version 1.12	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Removed UKGTN Illumina TruGenome Clinical Sequencing Services Radboud University Medical Center, Nijmegen Phenotypes Diabetes mellitus, transient neonatal, 1, 601410 Transient Neonatal Diabetes, Recessive Neonatal Diabetes Tags curated_removed
Green ZFP57 in IUGR and IGF abnormalities Level 3: Growth hormone disorders Level 2: Endocrine disorders Version 1.70	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Literature Phenotypes Phenotypes consistent with hypomethylation at multiple imprinted loci
Green ZFP57 in Diabetes with additional phenotypes suggestive of a monogenic aetiology Level 3: Disorders of unusual phenotypes Level 2: Endocrine disorders Version 1.68	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green UKGTN Illumina TruGenome Clinical Sequencing Services Radboud University Medical Center, Nijmegen Phenotypes Diabetes mellitus, transient neonatal, 1, 601410 Transient Neonatal Diabetes, Recessive Transient Neonatal Diabetes
Green ZFP57 in Neonatal diabetes Level 2: Endocrinology Version 5.17 Latest signed off version: v5.0 (7 Aug 2024)	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS Expert Review Green Eligibility statement prior genetic testing UKGTN Illumina TruGenome Clinical Sequencing Services Radboud University Medical Center, Nijmegen Phenotypes Diabetes mellitus, transient neonatal, 1, OMIM:601410
Green ZFP57 in Familial diabetes Level 3: Disorders of unusual phenotypes Level 2: Endocrine disorders Version 1.68	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS Expert Review Green UKGTN Radboud University Medical Center, Nijmegen Illumina TruGenome Clinical Sequencing Services Phenotypes Transient Neonatal Diabetes, Recessive Diabetes mellitus, transient neonatal, 1, 601410
Green ZFP57 in Monogenic diabetes Level 2: Endocrinology Version 3.8 Latest signed off version: v3.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS Expert Review Green Phenotypes transient neonatal diabetes mellitus (disease), MONDO:0020525 Diabetes mellitus, transient neonatal, 1, OMIM:601410
Green ZFP57 in Fetal anomalies Level 2: Fetal (including NIPD) Version 6.140 Latest signed off version: v6.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources PAGE DD-Gene2Phenotype Expert Review Green Phenotypes DIABETES MELLITUS, 6Q24-RELATED TRANSIENT NEONATAL
Green ZFP57 in DDG2P Version 6.424 Latest signed off version: v6.0 (30 Apr 2025) Component of the following Super Panels: Paediatric disorders	review	BIALLELIC, autosomal or pseudoautosomal	Sources DD-Gene2Phenotype Expert Review Green Phenotypes DIABETES MELLITUS, 6Q24-RELATED TRANSIENT NEONATAL 601410
Amber ZFP57 in Intellectual disability Level 2: Developmental disorders Version 9.279 Latest signed off version: v9.0 (30 Apr 2025) Component of the following Super Panels: Childhood onset leukodystrophy Hypotonic infant Paediatric disorders	review	BIALLELIC, autosomal or pseudoautosomal	Sources Victorian Clinical Genetics Services Expert Review Amber BRIDGE study SPEED NEURO Tier1 Gene Phenotypes Diabetes mellitus, transient neonatal, 1, 601410
Amber ZFP57 in Multi locus imprinting disorders Level 2: Endocrinology Version 1.18 Latest signed off version: v1.2 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber Expert list Phenotypes {Diabetes mellitus, transient neonatal 1}, OMIM:601410 Multi-locus imprinting disturbance (MLID) Tags to_be_confirmed_NHSE
Green ZFP57 in Monogenic short stature Level 2: Endocrinology Version 1.31 Latest signed off version: v1.0 (7 Aug 2024)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Phenotypes Diabetes mellitus, transient neonatal 1, OMIM:601410