1. Genes and Genomic Entities
  2. ZNFX1

ZNFX1

zinc finger NFX1-type containing 1
Gene2Phenotype

3 panels

Panel Reviews Mode of inheritance Details
3 panels
Green ZNFX1 in Primary immunodeficiency or monogenic inflammatory bowel disease


Level 2: Immunology
Version 8.88
Latest signed off version: v8.0 (30 Apr 2025)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Literature
Phenotypes
  • Immunodeficiency 91 and hyperinflammation, OMIM:619644
Green ZNFX1 in Early onset or syndromic epilepsy


Level 2: Neurology
Version 8.167
Latest signed off version: v8.0 (30 Apr 2025)

Component of the following Super Panels:

  • Paediatric disorders
  • Unexplained death in infancy and sudden unexplained death in childhood

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • NHS GMS
    • Literature
    Phenotypes
    • Immunodeficiency 91 and hyperinflammation, OMIM:619644
    • immunodeficiency 91 and hyperinflammation, MONDO:0030491
    Green ZNFX1 in Intellectual disability


    Level 2: Developmental disorders
    Version 9.345
    Latest signed off version: v9.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Childhood onset leukodystrophy
  • Hypotonic infant
  • Paediatric disorders

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • NHS GMS
    • Literature
    Phenotypes
    • Immunodeficiency 91 and hyperinflammation, OMIM:619644
    • immunodeficiency 91 and hyperinflammation, MONDO:0030491