KLC4

kinesin light chain 4
Gene2Phenotype

4 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 4 panels
Red KLC4 in Hereditary spastic paraplegia Level 3: Motor Disorders of the CNS Level 2: Neurology and neurodevelopmental disorders Version 1.316	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Red Literature Phenotypes spastic paraplegia progressive complicated spastic paraplegia
Red KLC4 in Childhood onset hereditary spastic paraplegia Level 2: Neurology Version 9.1 Latest signed off version: v9.0 (6 May 2026)	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS Yorkshire and North East GLH Expert Review Red Literature Phenotypes spastic paraplegia progressive complicated spastic paraplegia
Red KLC4 in Adult onset hereditary spastic paraplegia Level 2: Neurology Version 6.11 Latest signed off version: v6.10 (6 May 2026) Component of the following Super Panels: Adult-onset neurological disorders	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS Yorkshire and North East GLH South West GLH Phenotypes spastic paraplegia progressive complicated spastic paraplegia
Red KLC4 in Adult onset neurodegenerative disorder Level 2: Neurology Version 9.1 Latest signed off version: v9.0 (6 May 2026) Component of the following Super Panels: Adult-onset neurological disorders	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources NHS GMS Yorkshire and North East GLH Expert Review Red Expert list Phenotypes spastic paraplegia progressive complicated spastic paraplegia