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[
{
"created": "2022-11-30T14:25:51.307971Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "3.1",
"user_name": "Eleanor Williams",
"item_type": "panel",
"text": "Panel version 3.0 has been signed off on 2022-11-30",
"entity_name": null,
"entity_type": null
},
{
"created": "2022-11-30T14:25:12.208518Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "3.0",
"user_name": "Eleanor Williams",
"item_type": "panel",
"text": "promoted panel to version 3.0",
"entity_name": null,
"entity_type": null
},
{
"created": "2022-03-03T14:04:43.553333Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.13",
"user_name": "Ivone Leong",
"item_type": "entity",
"text": "Tag for-review was removed from gene: TTR.",
"entity_name": "TTR",
"entity_type": "gene"
},
{
"created": "2022-03-03T14:04:13.104510Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.13",
"user_name": "Ivone Leong",
"item_type": "entity",
"text": "commented on gene: TTR: The rating of this gene has been updated following NHS Genomic Medicine Service approval.",
"entity_name": "TTR",
"entity_type": "gene"
},
{
"created": "2022-03-03T14:04:09.422278Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.12",
"user_name": "Ivone Leong",
"item_type": "entity",
"text": "Source Expert Review Green was added to TTR.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "TTR",
"entity_type": "gene"
},
{
"created": "2022-02-07T15:12:14.872559Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.11",
"user_name": "Arina Puzriakova",
"item_type": "entity",
"text": "Publications for gene: ALB were set to 29163366; 8064810; 24646103; 27834068",
"entity_name": "ALB",
"entity_type": "gene"
},
{
"created": "2022-02-07T15:12:07.527553Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.10",
"user_name": "Arina Puzriakova",
"item_type": "entity",
"text": "Added comment: Comment on mode of inheritance: Most cases of familial dysalbuminaemic hyperthyroxinaemia (FDH) are associated with heterozygous variants in the albumin gene. Only one report to date of a biallelic variant causing FDH (PMID: 29676214) where the proband displayed a greater increase in T4 relative to that observed in heterozygous family members. As there are no further biallelic FDH cases and the recessive phenotype of congenital analbuminemia (also associated with this gene) is not relevant to this panel, the MOI of 'monoallelic' inheritance will be maintained at this time.",
"entity_name": "ALB",
"entity_type": "gene"
},
{
"created": "2022-02-07T15:12:07.486135Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.10",
"user_name": "Arina Puzriakova",
"item_type": "entity",
"text": "Mode of inheritance for gene: ALB was changed from MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown",
"entity_name": "ALB",
"entity_type": "gene"
},
{
"created": "2022-02-07T14:46:14.343324Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.9",
"user_name": "Arina Puzriakova",
"item_type": "entity",
"text": "Phenotypes for gene: ALB were changed from Familial dysalbuminaemic hyperthyroxinaemia; [Dysalbuminemic hyperthyroxinemia], 615999 to Familial dysalbuminaemic hyperthyroxinaemia; [Dysalbuminemic hyperthyroxinemia], OMIM:615999; ?[Dysalbuminemic hypertriiodothyroninemia], OMIM:615999",
"entity_name": "ALB",
"entity_type": "gene"
},
{
"created": "2021-08-24T12:23:21.369237Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.8",
"user_name": "Arina Puzriakova",
"item_type": "entity",
"text": "Phenotypes for gene: SLC16A2 were changed from Monocarboxylate transporter 8 (MCT8) defect; Allan-Herndon-Dudley syndrome; Allan_Herndon_Dudley Syndrome; AHDS; 300523; Allan-Herndon-Dudley syndrome, 300523; Allan-Herndon-Dudley Syndrome; ALLAN-HERNDON-DUDLEY SYNDROME; ALLAN-HERNDON SYNDROME; MONOCARBOXYLATE TRANSPORTER 8 DEFICIENCY; TRIIODOTHYRONINE RESISTANCE; T3 RESISTANCE; MENTAL RETARDATION, X-LINKED, WITH HYPOTONIA; MENTAL RETARDATION AND MUSCULAR ATROPHY; mental retardation, X-linked, with hypotonia; MCT8 (SLC16A2)-specific thyroid hormone cell transporter deficiency; monocarboxylate transporter 8 (MCT8) deficiency to Allan-Herndon-Dudley syndrome, OMIM:300523",
"entity_name": "SLC16A2",
"entity_type": "gene"
},
{
"created": "2020-10-20T15:12:06.153090Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.7",
"user_name": "Arina Puzriakova",
"item_type": "entity",
"text": "Classified gene: TTR as Amber List (moderate evidence)",
"entity_name": "TTR",
"entity_type": "gene"
},
{
"created": "2020-10-20T15:12:06.149507Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.7",
"user_name": "Arina Puzriakova",
"item_type": "entity",
"text": "Added comment: Comment on list classification: Changed rating from Green to Amber so that Green genes on this panel reflect the NHS signed-off version. This will be reviewed at the next GMS panel update (added 'for-review' tag).",
"entity_name": "TTR",
"entity_type": "gene"
},
{
"created": "2020-10-20T15:12:06.123009Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.7",
"user_name": "Arina Puzriakova",
"item_type": "entity",
"text": "Gene: ttr has been classified as Amber List (Moderate Evidence).",
"entity_name": "TTR",
"entity_type": "gene"
},
{
"created": "2020-10-20T15:11:58.721723Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.6",
"user_name": "Arina Puzriakova",
"item_type": "entity",
"text": "Tag for-review tag was added to gene: TTR.",
"entity_name": "TTR",
"entity_type": "gene"
},
{
"created": "2020-07-08T14:49:16.435882Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.6",
"user_name": "Eleanor Williams",
"item_type": "entity",
"text": "Tag ensembl_ids_known_missing tag was added to gene: TRU-TCA1-1.",
"entity_name": "TRU-TCA1-1",
"entity_type": "gene"
},
{
"created": "2020-07-08T14:48:54.044646Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.6",
"user_name": "Eleanor Williams",
"item_type": "entity",
"text": "commented on gene: TRU-TCA1-1",
"entity_name": "TRU-TCA1-1",
"entity_type": "gene"
},
{
"created": "2020-05-05T09:47:56.408040Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.6",
"user_name": "Ivone Leong",
"item_type": "entity",
"text": "Classified gene: TTR as Green List (high evidence)",
"entity_name": "TTR",
"entity_type": "gene"
},
{
"created": "2020-05-05T09:47:56.404114Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.6",
"user_name": "Ivone Leong",
"item_type": "entity",
"text": "Added comment: Comment on list classification: Based on expert review by David Halsall (Cambridge University Hospitals Trust), there is enough evidence to support a gene-disease association for TTR. Therefore this gene has been given Green status.",
"entity_name": "TTR",
"entity_type": "gene"
},
{
"created": "2020-05-05T09:47:56.378044Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.6",
"user_name": "Ivone Leong",
"item_type": "entity",
"text": "Gene: ttr has been classified as Green List (High Evidence).",
"entity_name": "TTR",
"entity_type": "gene"
},
{
"created": "2020-05-05T09:35:14.054365Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.5",
"user_name": "Ivone Leong",
"item_type": "entity",
"text": "Phenotypes for gene: TTR were changed from # 145680 HYPERTHYROXINEMIA, DYSTRANSTHYRETINEMIC; DTTRH to [Dystransthyretinemic hyperthyroxinemia], 145680; DTTRH",
"entity_name": "TTR",
"entity_type": "gene"
},
{
"created": "2020-05-05T09:34:26.074941Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.4",
"user_name": "Ivone Leong",
"item_type": "entity",
"text": "Publications for gene: TTR were set to PMID: 31590893; 26522458",
"entity_name": "TTR",
"entity_type": "gene"
},
{
"created": "2020-03-30T11:21:26.628566Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.3",
"user_name": "david halsall",
"item_type": "entity",
"text": "gene: TTR was added\ngene: TTR was added to Hyperthyroidism. Sources: Literature\nMode of inheritance for gene: TTR was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown\nPublications for gene: TTR were set to PMID: 31590893; 26522458\nPhenotypes for gene: TTR were set to # 145680 HYPERTHYROXINEMIA, DYSTRANSTHYRETINEMIC; DTTRH\nPenetrance for gene: TTR were set to unknown\nMode of pathogenicity for gene: TTR was set to Other\nReview for gene: TTR was set to GREEN\nAdded comment: Specific gain of function sequence variants in TTE can cause method dependent factitious increases in serum free thyroxine when measured by commercial competive immunoassay methods. V30M, S77Y, I84S, V122I have been reported. \r\nThese varients need to be considered separately from loss of function at the locus which is associated with an amyloidogenic phenotype (familial transthyretin amyloidosis). \nSources: Literature",
"entity_name": "TTR",
"entity_type": "gene"
},
{
"created": "2020-02-19T16:47:15.625749Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.3",
"user_name": "Sarah Leigh",
"item_type": "panel",
"text": "Panel version has been signed off",
"entity_name": null,
"entity_type": null
},
{
"created": "2019-07-31T15:03:48.409172Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "2.0",
"user_name": "Ivone Leong",
"item_type": "panel",
"text": "promoted panel to version 2.0",
"entity_name": null,
"entity_type": null
},
{
"created": "2019-07-31T15:02:50.156510Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "1.9",
"user_name": "Ivone Leong",
"item_type": "panel",
"text": "List of related panels changed from Resistance to thyroid hormone to Resistance to thyroid hormone; R182\nPanel types changed to Rare Disease 100K; GMS Rare Disease Virtual; GMS signed-off",
"entity_name": null,
"entity_type": null
},
{
"created": "2019-07-11T12:43:15.511488Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "1.8",
"user_name": "Ivone Leong",
"item_type": "entity",
"text": "reviewed gene: ALB: Rating: GREEN; Mode of pathogenicity: ; Publications: 27834068, 24646103, 8064810, 29163366; Phenotypes: ; Mode of inheritance: ",
"entity_name": "ALB",
"entity_type": "gene"
},
{
"created": "2019-07-11T12:43:15.495997Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "1.8",
"user_name": "Ivone Leong",
"item_type": "entity",
"text": "reviewed gene: TSHR: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: ",
"entity_name": "TSHR",
"entity_type": "gene"
},
{
"created": "2019-07-11T12:43:15.478240Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "1.8",
"user_name": "krishna chatterjee",
"item_type": "entity",
"text": "reviewed gene: TSHR: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: Congenital, nonautoimmune hyperthyroidism; Mode of inheritance: ",
"entity_name": "TSHR",
"entity_type": "gene"
},
{
"created": "2019-07-11T12:43:15.467253Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "1.8",
"user_name": "krishna chatterjee",
"item_type": "entity",
"text": "reviewed gene: THRA: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: Resistance to Thyroid Hormone alpha; Mode of inheritance: ",
"entity_name": "THRA",
"entity_type": "gene"
},
{
"created": "2019-07-11T12:43:15.456026Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "1.8",
"user_name": "krishna chatterjee",
"item_type": "entity",
"text": "reviewed gene: THRB: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: Resistance to Thyroid Hormone beta; Mode of inheritance: ",
"entity_name": "THRB",
"entity_type": "gene"
},
{
"created": "2019-07-11T12:43:15.445431Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "1.8",
"user_name": "krishna chatterjee",
"item_type": "entity",
"text": "reviewed gene: SECISBP2: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: Selenoprotein deficiency; Mode of inheritance: ",
"entity_name": "SECISBP2",
"entity_type": "gene"
},
{
"created": "2019-07-11T12:43:15.435126Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "1.8",
"user_name": "krishna chatterjee",
"item_type": "entity",
"text": "reviewed gene: SLC16A2: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: Allan Herndon Dudley Syndrome; Mode of inheritance: ",
"entity_name": "SLC16A2",
"entity_type": "gene"
},
{
"created": "2019-07-11T12:43:15.420688Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "1.8",
"user_name": "krishna chatterjee",
"item_type": "entity",
"text": "reviewed gene: ALB: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: Familial dysalbuminaemic hyperthyroxinaemia; Mode of inheritance: ",
"entity_name": "ALB",
"entity_type": "gene"
},
{
"created": "2019-07-11T12:42:36.085681Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "1.7",
"user_name": "Ivone Leong",
"item_type": "entity",
"text": "gene: TSHR was added\ngene: TSHR was added to Hyperthyroidism. Sources: Expert list,Expert Review Green\nMode of inheritance for gene: TSHR was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown\nPhenotypes for gene: TSHR were set to Congenital, nonautoimmune hyperthyroidism; Hyperthyroidism, nonautoimmune, 609152",
"entity_name": "TSHR",
"entity_type": "gene"
},
{
"created": "2019-07-11T12:42:36.040413Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "1.7",
"user_name": "Ivone Leong",
"item_type": "entity",
"text": "Source Expert list was added to THRA.",
"entity_name": "THRA",
"entity_type": "gene"
},
{
"created": "2019-07-11T12:42:35.984625Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "1.7",
"user_name": "Ivone Leong",
"item_type": "entity",
"text": "Source Expert list was added to THRB.",
"entity_name": "THRB",
"entity_type": "gene"
},
{
"created": "2019-07-11T12:42:35.937084Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "1.7",
"user_name": "Ivone Leong",
"item_type": "entity",
"text": "Source Expert list was added to SECISBP2.",
"entity_name": "SECISBP2",
"entity_type": "gene"
},
{
"created": "2019-07-11T12:42:35.880822Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "1.7",
"user_name": "Ivone Leong",
"item_type": "entity",
"text": "Source Expert list was added to SLC16A2.",
"entity_name": "SLC16A2",
"entity_type": "gene"
},
{
"created": "2019-07-11T12:42:35.827278Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "1.7",
"user_name": "Ivone Leong",
"item_type": "entity",
"text": "gene: ALB was added\ngene: ALB was added to Hyperthyroidism. Sources: Expert list,Expert Review Green\nMode of inheritance for gene: ALB was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown\nPublications for gene: ALB were set to 29163366; 8064810; 24646103; 27834068\nPhenotypes for gene: ALB were set to Familial dysalbuminaemic hyperthyroxinaemia; [Dysalbuminemic hyperthyroxinemia], 615999",
"entity_name": "ALB",
"entity_type": "gene"
},
{
"created": "2018-11-12T14:14:08.319266Z",
"panel_name": "Hyperthyroidism",
"panel_id": 236,
"panel_version": "1.5",
"user_name": "Ellen McDonagh",
"item_type": "panel",
"text": "Panel name changed from Resistance to thyroid hormone to Hyperthyroidism\nList of related panels changed from to Resistance to thyroid hormone\nPanel types changed to Rare Disease 100K; GMS Rare Disease Virtual",
"entity_name": null,
"entity_type": null
},
{
"created": "2018-08-08T07:52:36.880125Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Ellen McDonagh",
"item_type": "entity",
"text": "commented on gene: SLC16A2",
"entity_name": "SLC16A2",
"entity_type": "gene"
},
{
"created": "2018-08-08T07:51:57.859308Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Ellen McDonagh",
"item_type": "entity",
"text": "commented on gene: THRB",
"entity_name": "THRB",
"entity_type": "gene"
},
{
"created": "2018-08-08T07:49:29.799164Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Ellen McDonagh",
"item_type": "entity",
"text": "commented on gene: THRA",
"entity_name": "THRA",
"entity_type": "gene"
},
{
"created": "2017-03-15T15:49:58.620000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "panel",
"text": "promoted panel to version 1",
"entity_name": null,
"entity_type": null
},
{
"created": "2017-03-15T15:44:51.816000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "marked TRU-TCA1-1 as ready",
"entity_name": "TRU-TCA1-1",
"entity_type": "gene"
},
{
"created": "2017-03-15T15:44:34.762000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "marked THRB as ready",
"entity_name": "THRB",
"entity_type": "gene"
},
{
"created": "2017-03-15T15:44:17.574000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "marked THRA as ready",
"entity_name": "THRA",
"entity_type": "gene"
},
{
"created": "2017-03-15T15:44:00.454000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "marked SLC16A2 as ready",
"entity_name": "SLC16A2",
"entity_type": "gene"
},
{
"created": "2017-03-15T15:43:42.676000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "marked SECISBP2 as ready",
"entity_name": "SECISBP2",
"entity_type": "gene"
},
{
"created": "2017-03-15T15:29:19.375000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "classified TRU-TCA1-1 as red",
"entity_name": "TRU-TCA1-1",
"entity_type": "gene"
},
{
"created": "2017-03-15T15:26:07.573000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "classified THRA as green",
"entity_name": "THRA",
"entity_type": "gene"
},
{
"created": "2017-03-15T12:26:07.941000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "classified SECISBP2 as green",
"entity_name": "SECISBP2",
"entity_type": "gene"
},
{
"created": "2017-03-15T12:25:06.146000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "edited their review of TRU-TCA1-1",
"entity_name": "TRU-TCA1-1",
"entity_type": "gene"
},
{
"created": "2017-03-15T12:23:20.420000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "reviewed SLC16A2",
"entity_name": "SLC16A2",
"entity_type": "gene"
},
{
"created": "2017-03-15T12:23:01.109000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "reviewed THRB",
"entity_name": "THRB",
"entity_type": "gene"
},
{
"created": "2017-03-15T12:19:12.608000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "edited their review of THRA",
"entity_name": "THRA",
"entity_type": "gene"
},
{
"created": "2017-03-15T12:18:44.704000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "edited their review of SECISBP2",
"entity_name": "SECISBP2",
"entity_type": "gene"
},
{
"created": "2017-03-14T16:54:02.945000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "commented on THRA",
"entity_name": "THRA",
"entity_type": "gene"
},
{
"created": "2017-03-14T16:41:22.222000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "commented on SECISBP2",
"entity_name": "SECISBP2",
"entity_type": "gene"
},
{
"created": "2017-03-14T16:35:12.848000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "commented on TRU-TCA1-1",
"entity_name": "TRU-TCA1-1",
"entity_type": "gene"
},
{
"created": "2017-03-04T19:22:45.889000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "edited their review of TRU-TCA1-1",
"entity_name": "TRU-TCA1-1",
"entity_type": "gene"
},
{
"created": "2017-03-04T18:40:17.055000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "commented on TRU-TCA1-1",
"entity_name": "TRU-TCA1-1",
"entity_type": "gene"
},
{
"created": "2017-03-04T18:38:09.167000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "added TRU-TCA1-1 to panel",
"entity_name": "TRU-TCA1-1",
"entity_type": "gene"
},
{
"created": "2017-03-04T18:38:09.069000Z",
"panel_name": "Resistance to thyroid hormone",
"panel_id": 236,
"panel_version": null,
"user_name": "Louise Daugherty",
"item_type": "entity",
"text": "reviewed TRU-TCA1-1",
"entity_name": "TRU-TCA1-1",
"entity_type": "gene"
}
]