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Anaemias and red cell disorders

Gene: U2AF1

Red List (low evidence)

U2AF1 (U2 small nuclear RNA auxiliary factor 1)
EnsemblGeneIds (GRCh38): ENSG00000160201
EnsemblGeneIds (GRCh37): ENSG00000160201
OMIM: 191317, Gene2Phenotype
U2AF1 is in 1 panel

2 reviews

Ellen McDonagh (Genomics England Curator)

source: BRIDGE consortium (NIHRBR-RD)
Created: 22 Sep 2017, 12:42 p.m.

BRIDGE consortium (NIHRBR-RD)

Green List (high evidence)

Mode of inheritance
Unknown

Phenotypes
Acute myeloid leukaemia (AML); Myelodysplastic syndrome (MDS)

Variants in this GENE are reported as part of current diagnostic practice

Details

Mode of Inheritance
Unknown
Sources
  • Expert Review Red
Phenotypes
  • Acute myeloid leukaemia (AML)
  • Myelodysplastic syndrome (MDS)
OMIM
191317
Clinvar variants
Variants in U2AF1
Penetrance
Complete
Panels with this gene

History Filter Activity

22 Sep 2017, Gel status: 1

Gene classified by Genomics England curator

Ellen McDonagh (Genomics England Curator)

This gene has been classified as Red List (Low Evidence).

22 Sep 2017, Gel status: 2

clearsources

Ellen McDonagh (Genomics England Curator)

U2AF1All sources for gene: U2AF1 were removed

22 Sep 2017, Gel status: 2

Upload gene information

Ellen McDonagh (Genomics England Curator)

U2AF1 was added to Anaemias and red cell disorderspanel. Sources: Radboud University Medical Center, Nijmegen

22 Sep 2017, Gel status: 1

Upload gene information

Ellen McDonagh (Genomics England Curator)

U2AF1 was added to Anaemias and red cell disorderspanel. Sources: Emory Genetics Laboratory

16 Jan 2017, Gel status: 0

Approved Gene

Louise Daugherty (Genomics England Curator)

This proposed gene was validated and added to this panel

16 Jan 2017, Gel status: 0

Added New Source

BRIDGE consortium (NIHRBR-RD)

U2AF1 was added to Anaemias and red cell disorderspanel. Sources: BRIDGE consortium (NIHRBR-RD)

16 Jan 2017, Gel status: 0

Created

BRIDGE consortium (NIHRBR-RD)

U2AF1 was created by BRIDGE