This Panel is marked as Internal
Anaemias and red cell disorders
Gene: WRAP53
WRAP53 (WD repeat containing antisense to TP53)
EnsemblGeneIds (GRCh38): ENSG00000141499
EnsemblGeneIds (GRCh37): ENSG00000141499
OMIM: 612661, Gene2Phenotype
WRAP53 is in 13 panels
EnsemblGeneIds (GRCh38): ENSG00000141499
EnsemblGeneIds (GRCh37): ENSG00000141499
OMIM: 612661, Gene2Phenotype
WRAP53 is in 13 panels
Details
- Mode of Inheritance
- BIALLELIC, autosomal or pseudoautosomal
- Sources
-
- Radboud University Medical Center, Nijmegen
- Illumina TruGenome Clinical Sequencing Services
- UKGTN
- Expert list
- Phenotypes
-
- Inherited Bone Marrow Failure Syndromes
- Dyskeratosis congenita
- Dyskeratosis congenita, autosomal recessive 3, 613988
- Dyskeratosis Congenita, Recessive
- Dyskeratosis Congenita, Autosomal Recessive, 3
- OMIM
- 612661
- Clinvar variants
- Variants in WRAP53
- Penetrance
- Complete
- Panels with this gene
-
- Haematological malignancies for rare disease
- Cytopenia - NOT Fanconi anaemia
- Cytopenias and congenital anaemias
- Primary immunodeficiency or monogenic inflammatory bowel disease
- Ductal plate malformation
- Childhood solid tumours
- DDG2P
- Adult solid tumours cancer susceptibility
- Haematological malignancies cancer susceptibility
- Intellectual disability
- Fetal anomalies
- Pigmentary skin disorders
- COVID-19 research
History Filter Activity
22 Jul 2016, Gel status: 3
Added New Source
Ellen McDonagh (Genomics England Curator)WRAP53 was added to Anaemias and red cell disorderspanel. Source: Radboud University Medical Center, Nijmegen WRAP53 was added to Anaemias and red cell disorderspanel. Source: Illumina TruGenome Clinical Sequencing Services
22 Jul 2016, Gel status: 0
Created
Ellen McDonagh (Genomics England Curator)WRAP53 was created by ellenmcdonagh
22 Jul 2016, Gel status: 1
Added New Source
Ellen McDonagh (Genomics England Curator)WRAP53 was added to Anaemias and red cell disorderspanel. Sources: UKGTN,Expert list