Familial tumours of the nervous system
Gene: LZTFL1EnsemblGeneIds (GRCh38): ENSG00000163818
EnsemblGeneIds (GRCh37): ENSG00000163818
OMIM: 606568, Gene2Phenotype
LZTFL1 is in 16 panels
2 reviews
Eleanor Williams (Genomics England Curator)
This gene has been removed from the panel as it is the incorrect gene. It has been replaced with LZTR1. This has been done with NHS Genomic Medicine Service approval.Created: 11 Oct 2023, 4:35 p.m. | Last Modified: 11 Oct 2023, 4:35 p.m.
Panel Version: 1.3
Achchuthan Shanmugasundram (Genomics England Curator)
LZTFL1 has been added to the panel for R221 Familial tumours of the nervous system with a green rating as agreed with the NHS Genomic Medicine Service.Created: 30 Jun 2023, 1:12 p.m. | Last Modified: 30 Jun 2023, 1:12 p.m.
Panel Version: 0.1
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Details
- Mode of Inheritance
- MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
- Sources
-
- Expert Review Removed
- NHS GMS
- Tags
- OMIM
- 606568
- Clinvar variants
- Variants in LZTFL1
- Penetrance
- None
- Panels with this gene
-
- Fetal anomalies
- Glaucoma (developmental)
- Primary ciliary disorders
- Rare multisystem ciliopathy disorders
- Intellectual disability
- Childhood onset dystonia, chorea or related movement disorder
- Renal ciliopathies
- Laterality disorders and isomerism
- Limb disorders
- Ophthalmological ciliopathies
- Retinal disorders
- COVID-19 research
- Familial tumours of the nervous system
- Skeletal ciliopathies
- Bardet Biedl syndrome
- Structural eye disease
History Filter Activity
Added Tag
Eleanor Williams (Genomics England Curator)Tag curated_removed tag was added to gene: LZTFL1.
Added New Source, Status Update
Eleanor Williams (Genomics England Curator)Source Expert Review Removed was added to LZTFL1. Rating Changed from Green List (high evidence) to No List (delete)
Created, Added New Source, Set mode of inheritance
Achchuthan Shanmugasundram (Genomics England Curator)gene: LZTFL1 was added gene: LZTFL1 was added to Familial tumours of the nervous system. Sources: NHS GMS,Expert Review Green Mode of inheritance for gene: LZTFL1 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown