Familial non syndromic congenital heart disease
Gene: FOXL1

FOXL1 (forkhead box L1)
EnsemblGeneIds (GRCh38): ENSG00000176678
EnsemblGeneIds (GRCh37): ENSG00000176678
OMIM: 603252, Gene2Phenotype
FOXL1 is in 1 panel

1 review

Alice Gardham (Genomics England)

Red List (low evidence)

No definite association with congenital heart disease. Not recognised on G2P
Created: 28 Nov 2016, 12:32 p.m.

Mode of inheritance
Unknown

Created: 28 Nov 2016, 12:32 p.m.

Panel version: 0.2

Details

Sources

Expert Review Red
Radboud University Medical Center, Nijmegen

Phenotypes

Hypoplastic left heart syndrome (Iascone (2012) Clin Genet 81,542)

OMIM

603252

Clinvar variants

Variants in FOXL1

Penetrance

Complete

Publications

DOI: 10.1111/j.1399-0004.2011.01674.x

Panels with this gene

Familial non syndromic congenital heart disease

History Filter Activity

26 Jan 2017, Gel status: 1

panel promoted to version 1

Alice Gardham (Genomics England)

Promoted to version 1 by Alice Gardham on 26th January

28 Nov 2016, Gel status: 1

Gene classified by Genomics England curator

Alice Gardham (Genomics England)

This gene has been classified as Red List (Low Evidence).

28 Nov 2016, Gel status: 1

Added New Source

Ellen McDonagh (Genomics England Curator)

FOXL1 was added to Familial non syndromic congenital heart diseasepanel. Sources: Radboud University Medical Center, Nijmegen

28 Nov 2016, Gel status: 0

Created