Intellectual disability update Jan 2018
Gene: GLRA2

GLRA2 (glycine receptor alpha 2)
EnsemblGeneIds (GRCh38): ENSG00000101958
EnsemblGeneIds (GRCh37): ENSG00000101958
OMIM: 305990, Gene2Phenotype
GLRA2 is in 2 panels

1 review

Sarah Leigh (Genomics England Curator)

Not associated with phenotype in OMIM or G2P. At least four missense variants and a micro-deletion reported in autism disorder syndrome cases.

Grozeva 2015 PMID 26350204 reports GLRA2 as a candidate ID gene
Created: 5 Mar 2018, 1:51 p.m.

Created: 5 Mar 2018, 1:51 p.m.

Panel version: 0.322

Details

Sources

Expert Review Red

Phenotypes

autism spectrum disorder

OMIM

305990

Clinvar variants

Variants in GLRA2

Penetrance

None

Publications

Panels with this gene

History Filter Activity

5 Mar 2018, Gel status: 1

Set Phenotypes

Sarah Leigh (Genomics England Curator)

Phenotypes for GLRA2 were set to autism spectrum disorder

5 Mar 2018, Gel status: 1

Set publications

Sarah Leigh (Genomics England Curator)

Publications for GLRA2 were set to 28588452; 26370147; 29057625

18 Dec 2017, Gel status: 1

Added New Source

Ellen McDonagh (Genomics England Curator)

GLRA2 was added to Intellectual disability update Jan 2018 panel. Sources: Expert Review Red