Intellectual disability update Jan 2018
Gene: GRB14

GRB14 (growth factor receptor bound protein 14)
EnsemblGeneIds (GRCh38): ENSG00000115290
EnsemblGeneIds (GRCh37): ENSG00000115290
OMIM: 601524, Gene2Phenotype
GRB14 is in 1 panel

1 review

Louise Daugherty (Genomics England Curator)

Red List (low evidence)

Comment on publications: Candidate intellectual disability gene suggested by Grozeva et al, (2015) PMID: 26350204
Created: 1 Mar 2018, 2:19 p.m.

This is a candidate intellectual disability gene from Grozeva et al., (2015) PMID: 26350204, however no evidence to date has been found to support the association between variants of this gene and an observed intellectual disability phenotype.

This gene is also not currently a DD gene in Gene2Phenotype.
Created: 1 Mar 2018, 2:18 p.m.

Created: 1 Mar 2018, 2:18 p.m.

Panel version: 0.233

Details

Sources

Expert Review Red

OMIM

601524

Clinvar variants

Variants in GRB14

Penetrance

None

Publications

26350204

Panels with this gene

Intellectual disability

History Filter Activity

1 Mar 2018, Gel status: 1

Set publications

Louise Daugherty (Genomics England Curator)

Publications for GRB14 were set to 26350204

18 Dec 2017, Gel status: 1

Added New Source

Ellen McDonagh (Genomics England Curator)

GRB14 was added to Intellectual disability update Jan 2018 panel. Sources: Expert Review Red

18 Dec 2017, Gel status: 1

Created

Ellen McDonagh (Genomics England Curator)

GRB14 was created by Ellen McDonagh

Intellectual disability update Jan 2018 Gene: GRB14