Intellectual disability update Jan 2018
Gene: MAPT

MAPT (microtubule associated protein tau)
EnsemblGeneIds (GRCh38): ENSG00000186868
EnsemblGeneIds (GRCh37): ENSG00000186868
OMIM: 157140, Gene2Phenotype
MAPT is in 5 panels

1 review

Eleanor Williams (Genomics England Curator)

Comment on list classification: Associated with Dementia, frontotemporal, with or without parkinsonism (MIM: 600274), Pick disease (MIM:172700), Supranuclear palsy, progressive (MIM: 601104), Supranuclear palsy, progressive atypical (MIM:260540), {Parkinson disease, susceptibility to} (MIM: 168600) in OMIM but no evidence found of association with Intellectual Disability in OMIM, Gene2Phenotype or PubMed searches.
Created: 27 Feb 2018, 4:19 p.m.

Created: 27 Feb 2018, 4:19 p.m.

Panel version: 0.141

Details

Sources

Expert Review Red
BRIDGE study SPEED NEURO Tier1 Gene

OMIM

157140

Clinvar variants

Variants in MAPT

Penetrance

None

Panels with this gene

History Filter Activity

27 Feb 2018, Gel status: 1

Gene classified by Genomics England curator

Eleanor Williams (Genomics England Curator)

This gene has been classified as Red List (Low Evidence).

18 Dec 2017, Gel status: 2

Added New Source

Ellen McDonagh (Genomics England Curator)

MAPT was added to Intellectual disability update Jan 2018 panel. Sources: BRIDGE study SPEED NEURO Tier1 Gene,Expert Review Amber