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  2. Structural eye disease
  3. ASB10
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Structural eye disease

Gene: ASB10

Red List (low evidence)
ASB10 (ankyrin repeat and SOCS box containing 10)
EnsemblGeneIds (GRCh38): ENSG00000146926
EnsemblGeneIds (GRCh37): ENSG00000146926
OMIM: 615054, Gene2Phenotype
ASB10 is in 2 panels

2 reviews

Nicola Ragge (Birmingham Women's and Children's NHS Foundation Hospital Trust)

Red List (low evidence)

glaucoma gene, can't find any evidence that it is associated with structural eye disease. All cases adult-onset glaucoma
Created: 19 Jun 2019, 3:32 p.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
GLAUCOMA 1, OPEN ANGLE, F; 603383

Created: 19 Jun 2019, 3:32 p.m.

Panel version: 0.76

Ivone Leong (Genomics England Curator)

Red List (low evidence)

Submitted on behalf of Professor Nicola Ragge (Wessex and West Midlands GLH). glaucoma gene, can't find any evidence that it is associated with structural eye disease. All cases adult-onset glaucoma
Created: 17 Apr 2019, 3:30 p.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
GLAUCOMA 1, OPEN ANGLE, F, 603383

Created: 17 Apr 2019, 3:30 p.m.

Panel version: 0.38

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • NHS GMS
  • Expert Review Red
Phenotypes
  • Glaucoma 1, open angle, F, 603383
OMIM
615054
Clinvar variants
Variants in ASB10
Penetrance
None
Panels with this gene

History Filter Activity

17 Apr 2019, Gel status: 1

Set Phenotypes

Ivone Leong (Genomics England Curator)

Phenotypes for gene: ASB10 were changed from Glaucoma 1, open angle, F, 603383; GLAUCOMA 1, OPEN ANGLE, F, 603383 to Glaucoma 1, open angle, F, 603383

17 Apr 2019, Gel status: 1

Added New Source, Set mode of inheritance, Set Phenotypes

Ivone Leong (Genomics England Curator)

Source NHS GMS was added to ASB10. Mode of inheritance for gene ASB10 was changed from to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Added phenotypes GLAUCOMA 1, OPEN ANGLE, F, 603383 for gene: ASB10

3 Jan 2019, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Ellen McDonagh (Genomics England Curator)

gene: ASB10 was added gene: ASB10 was added to Structural eye disease. Sources: Expert Review Red Mode of inheritance for gene: ASB10 was set to Phenotypes for gene: ASB10 were set to Glaucoma 1, open angle, F, 603383