Structural eye disease
Gene: VCAN

VCAN (versican)
EnsemblGeneIds (GRCh38): ENSG00000038427
EnsemblGeneIds (GRCh37): ENSG00000038427
OMIM: 118661, Gene2Phenotype
VCAN is in 4 panels

2 reviews

Nicola Ragge (Birmingham Women's and Children's NHS Foundation Hospital Trust)

Red List (low evidence)

retinal gene, can't find any evidence that it is associated with structural eye disease
Created: 19 Jun 2019, 3:32 p.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
Wagner syndrome 1; 143200

Created: 19 Jun 2019, 3:32 p.m.

Panel version: 0.76

Ivone Leong (Genomics England Curator)

Red List (low evidence)

Submitted on behalf of Professor Nicola Ragge (Wessex and West Midlands GLH). retinal gene, can't find any evidence that it is associated with structural eye disease
Created: 17 Apr 2019, 3:30 p.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
Wagner syndrome 1, 143200

Created: 17 Apr 2019, 3:30 p.m.

Panel version: 0.48

Details

Mode of Inheritance

MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Sources

NHS GMS
Expert Review Red

Phenotypes

Wagner syndrome 1, 143200
Eye Disorders

OMIM

118661

Clinvar variants

Variants in VCAN

Penetrance

None

Panels with this gene

History Filter Activity

17 Apr 2019, Gel status: 1

Added New Source, Set mode of inheritance, Set Phenotypes

Ivone Leong (Genomics England Curator)

Source NHS GMS was added to VCAN. Mode of inheritance for gene VCAN was changed from to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Added phenotypes Wagner syndrome 1, 143200 for gene: VCAN

3 Jan 2019, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Ellen McDonagh (Genomics England Curator)

gene: VCAN was added gene: VCAN was added to Structural eye disease. Sources: Expert Review Red Mode of inheritance for gene: VCAN was set to Phenotypes for gene: VCAN were set to Eye Disorders

Structural eye disease Gene: VCAN