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This Panel is marked as Deleted

Test panel testing 2020-07-27 (Version 1.15)

Description
Test panel for release 3.1.2 of PanelApp
Panel Activity

6 reviewers

  • Ellen McDonagh (Genomics England Curator)

    Group: Other
    Workplace: Other

  • Sarah Leigh (Genomics England Curator)

    Group: Other
    Workplace: Other

  • Eleanor Williams (Genomics England Curator)

    Group: Other
    Workplace: Other

  • Ioannis Sarantitis (EUROPAC)

    Group: Other
    Workplace: Other clinical service

  • Ivone Leong (Genomics England Curator)

    Group: Other
    Workplace: Other

  • Reviewer Test (GenomicsEnglandTesting)

    Group: Other
    Workplace: Other

10 Entities

10 reviewed, 2 green

List Entity Reviews Mode of inheritance Details
10 Entitiess
Green List (high evidence)
ALX4
1 review
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • NHS GMS
Phenotypes
  • Parietal foramina 2, (AD), 609597
  • Frontonasal dysplasia 2, (AR), 613451
  • Parietal foramina
Tags
  • watchlist
Green List (high evidence)
5p15 terminal (Cri du chat syndrome) region Loss
ISCA-37390-Loss
Region
2 reviews
1 green
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review
  • Expert Review Green
Tags
  • cnv
Amber List (moderate evidence)
ARSB
2 reviews
1 red
Other
Sources
  • Expert Review Amber
  • NHS GMS
Phenotypes
  • Mucopolysaccharidosis VI (MPS6) 253200
Tags
Amber List (moderate evidence)
NOP56_GGCCTG
STR
1 review
1 green
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert list
  • Expert Review Amber
Phenotypes
  • Spinocerebellar ataxia 36 614153
Tags
  • STR
Amber List (moderate evidence)
PRSS1
5 reviews
4 green
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Expert Review Amber
  • NHS GMS
Tags
Red List (low evidence)
ALX3
1 review
Not set
Sources
  • Expert Review Red
  • NHS GMS
Phenotypes
  • Frontonasal dysplasia type 1 (frontorhiny)
Tags
No list
ABCC9
2 reviews
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert list
  • Expert Review Removed
  • NHS GMS
Phenotypes
  • hypertrichotic osteochondrodysplasia - 239850 (Cantu syndrome)
Tags
No list
FMR1_CGG
STR
1 review
X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)
Sources
  • Expert list
Phenotypes
  • Fragile X syndrome 300624
Tags
No list
22q11.2 recurrent (DGS/VCFS) region (proximal, A-D) (includes TBX1) Gain
ISCA-37446-Gain
Region
1 review
1 green
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert list
Phenotypes
  • Intellectual disability and congenital abnormalities,Autism
Tags
No list
PRSS1_CAG
STR
2 reviews
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Other
Tags

Major version comments

  • 2020-07-27 11:31 Eleanor Williams (Genomics England Curator) promoted panel to 1.0
    promoting to version 1

Downloads

Download lists

  • Whole panel
  • Green list (high evidence)
  • Green and Amber Genes
  • Amber Genes
  • Red list (low evidence)

Download Version