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Date	Panel	Item	Activity
Filter activities 11 actions
07 Mar 2023	Hereditary spastic paraplegia, adult onset v2.16	ATL1	Achchuthan Shanmugasundram Publications for gene: ATL1 were set to 11685207; 15517445
13 May 2019	Hereditary spastic paraplegia, adult onset v0.146	ATL1	Louise Daugherty Deleted their comment
13 May 2019	Hereditary spastic paraplegia, adult onset v0.71	ATL1	Louise Daugherty Publications for gene: ATL1 were set to
13 May 2019	Hereditary spastic paraplegia, adult onset v0.54	ATL1	Louise Daugherty Source Yorkshire and North East GLH was added to ATL1.
09 May 2019	Hereditary spastic paraplegia, adult onset v0.53	ATL1	Louise Daugherty commented on gene: ATL1: Review and rating submitted byJames Polke (Neurogenetics Laboratory,Institute of Neurology, London), unless specified in the review comment, on behalf of London North GLH for GMS Neurology specialist test group.
03 May 2019	Hereditary spastic paraplegia, adult onset v0.52	ATL1	Nick Beauchamp reviewed gene: ATL1: Rating: GREEN; Mode of pathogenicity: None; Publications: 11685207, 15517445; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted; Current diagnostic: yes
25 Apr 2019	Hereditary spastic paraplegia, adult onset v0.6	ATL1	Louise Daugherty reviewed gene: ATL1: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
25 Apr 2019	Hereditary spastic paraplegia, adult onset v0.5	ATL1	James Polke reviewed gene: ATL1: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: Spastic paraplegia 3A, 182600 autosomal dominant, Spastic Paraplegia, Dominant, Neuropathy, hereditary sensory, type ID, 613708 ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
25 Apr 2019	Hereditary spastic paraplegia, adult onset v0.4	ATL1	Louise Daugherty Source Expert Review Green was added to ATL1. Mode of inheritance for gene ATL1 was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Added phenotypes Spastic paraplegia 3A, 182600 autosomal dominant; Spastic Paraplegia, Dominant; Neuropathy, hereditary sensory, type ID, 613708 for gene: ATL1 Rating Changed from Red List (low evidence) to Green List (high evidence)
24 Apr 2019	Hereditary spastic paraplegia, adult onset v0.3	ATL1	Louise Daugherty Source NHS GMS was added to ATL1.
24 Apr 2019	Hereditary spastic paraplegia, adult onset v0.2	ATL1	Louise Daugherty gene: ATL1 was added gene: ATL1 was added to Hereditary spastic paraplegia - adult onset. Sources: London North GLH Mode of inheritance for gene: ATL1 was set to