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Childhood onset hereditary spastic paraplegia v9.6 ATP1A3 Katherine Schon gene: ATP1A3 was added
gene: ATP1A3 was added to Childhood onset hereditary spastic paraplegia. Sources: Literature
Mode of inheritance for gene: ATP1A3 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Publications for gene: ATP1A3 were set to PMID: 37043503
Phenotypes for gene: ATP1A3 were set to spasticity; developmental delay; intellectual disability
Penetrance for gene: ATP1A3 were set to Complete
Review for gene: ATP1A3 was set to GREEN
Added comment: Recurrent de novo pathogenic variant reported in nine individuals with childhood onset of phenotypes resembling complex hereditary spastic paraplegia or idiopathic spastic cerebral palsy.
Sources: Literature