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Renal tubulopathies v5.10 ATP6V1B1 Eleanor Williams Tag Q2_25_ MOI was removed from gene: ATP6V1B1.
Tag Q2_25_ NHS_review was removed from gene: ATP6V1B1.
Renal tubulopathies v5.10 ATP6V1B1 Eleanor Williams commented on gene: ATP6V1B1: The mode of inheritance of this gene has been updated to BOTH monoallelic and biallelic, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.
Renal tubulopathies v5.9 ATP6V1B1 Eleanor Williams Mode of inheritance for gene ATP6V1B1 was changed from BIALLELIC, autosomal or pseudoautosomal to BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Renal tubulopathies v4.21 ATP6V1B1 Sarah Leigh Tag Q2_25_ MOI tag was added to gene: ATP6V1B1.
Tag Q2_25_ NHS_review tag was added to gene: ATP6V1B1.
Renal tubulopathies v4.21 ATP6V1B1 Sarah Leigh reviewed gene: ATP6V1B1: Rating: GREEN; Mode of pathogenicity: None; Publications: 39837581, 9916796, 12566520, 18798332; Phenotypes: Distal renal tubular acidosis 2 with progressive sensorineural hearing loss, OMIM:267300, renal tubular acidosis, distal, 2, with progressive sensorineural hearing loss, MONDO:0009968; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Renal tubulopathies v4.21 ATP6V1B1 Celia Duff-Farrier reviewed gene: ATP6V1B1: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID 39837581; Phenotypes: ; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal; Current diagnostic: yes
Renal tubulopathies v1.16 ATP6V1B1 Eleanor Williams reviewed gene: ATP6V1B1: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: Renal tubular acidosis with deafness MIM 267300; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal; Current diagnostic: yes
Renal tubulopathies v1.15 ATP6V1B1 Eleanor Williams Source NHS GMS was added to ATP6V1B1.
Rating Changed from Green List (high evidence) to Green List (high evidence)