Activity
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3 actions
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| NICE approved PARP inhibitor treatment v0.5 | BRCA2 | Eleanor Williams reviewed gene: BRCA2: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| NICE approved PARP inhibitor treatment v0.4 | BRCA2 |
Eleanor Williams Source Expert Review Green was added to BRCA2. Rating Changed from Red List (low evidence) to Green List (high evidence) |
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| NICE approved PARP inhibitor treatment v0.2 | BRCA2 |
Achchuthan Shanmugasundram gene: BRCA2 was added gene: BRCA2 was added to NICE approved PARP inhibitor treatment. Sources: NHS GMS Mode of inheritance for gene: BRCA2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Phenotypes for gene: BRCA2 were set to {Breast-ovarian cancer, familial, 2}, OMIM:612555; {Breast cancer, male, susceptibility to}, OMIM:114480; {Prostate cancer}, OMIM:176807 Review for gene: BRCA2 was set to GREEN Added comment: BRCA2 has been added to the panel for R444 NICE approved PARP inhibitor treatment with a green rating as agreed with the NHS Genomic Medicine Service. Sources: NHS GMS |
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