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Intellectual disability v8.210 C1QC Achchuthan Shanmugasundram Added comment: Comment on publications: PMID:39196411 was identified by the Genomics England Applied Machine Learning (ML) team in a Biocuration-ML project for identifying new gene-disease associations using Natural Language Processing (NLP) and Generative AI techniques.
Intellectual disability v8.210 C1QC Achchuthan Shanmugasundram Publications for gene: C1QC were set to 39196411
Intellectual disability v8.209 C1QC Achchuthan Shanmugasundram gene: C1QC was added
gene: C1QC was added to Intellectual disability. Sources: Literature
Mode of inheritance for gene: C1QC was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: C1QC were set to 39196411
Phenotypes for gene: C1QC were set to C1q deficiency 3, OMIM:620322
Review for gene: C1QC was set to RED
Added comment: PMID:39196411 reported 12 patients with C1q deficiency, of which one was identified with homozygous variant in C1QC gene (p.(Arg69Ter)). Intellectual impairment was reported in this patient.
Sources: Literature