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Paroxysmal central nervous system disorders v3.10 CNBP Sarah Leigh Tag currently-ngs-unreportable was removed from gene: CNBP.
Paroxysmal central nervous system disorders v1.36 CNBP Sarah Leigh commented on gene: CNBP
Paroxysmal central nervous system disorders v1.35 CNBP Eleanor Williams Mode of inheritance for gene CNBP was changed from Other to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Paroxysmal central nervous system disorders v1.23 CNBP Arina Puzriakova Added comment: Comment on mode of inheritance: Lack of phenotypic relevance for SNVs - nucleotide repeat expansion mechanism
Paroxysmal central nervous system disorders v1.23 CNBP Arina Puzriakova Mode of inheritance for gene: CNBP was changed from MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted to Other
Paroxysmal central nervous system disorders v1.6 CNBP Arina Puzriakova Mode of inheritance for gene: CNBP was changed from Other - please specifiy in evaluation comments to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Paroxysmal central nervous system disorders v1.5 CNBP Arina Puzriakova Tag nucleotide-repeat-expansion tag was added to gene: CNBP.
Tag currently-ngs-unreportable tag was added to gene: CNBP.
Paroxysmal central nervous system disorders v1.5 CNBP Arina Puzriakova Phenotypes for gene: CNBP were changed from Myotonia; MYOTONIC DYSTROPHY 2 (DM2) to Myotonic dystrophy 2, OMIM:602668; Myotonic dystrophy type 2, MONDO:0011266
Paroxysmal central nervous system disorders v0.140 CNBP Rebecca Foulger Marked gene: CNBP as ready
Paroxysmal central nervous system disorders v0.140 CNBP Rebecca Foulger Gene: cnbp has been classified as Red List (Low Evidence).
Paroxysmal central nervous system disorders v0.27 CNBP Rebecca Foulger Source NHS GMS was added to CNBP.
Paroxysmal central nervous system disorders v0.26 CNBP Rebecca Foulger commented on gene: CNBP: Review and rating from James Polke (Neurogenetics Laboratory, Institute of Neurology, London) was collated (February 2019) on behalf of London North GLH for the GMS Neurology specialist test group.
Paroxysmal central nervous system disorders v0.25 CNBP James Polke reviewed gene: CNBP: Rating: RED; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Paroxysmal central nervous system disorders v0.24 CNBP Rebecca Foulger Source London North GLH was added to CNBP.
Paroxysmal central nervous system disorders v0.23 CNBP Rebecca Foulger reviewed gene: CNBP: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Paroxysmal central nervous system disorders v0.22 CNBP Tracy Lester reviewed gene: CNBP: Rating: RED; Mode of pathogenicity: ; Publications: ; Phenotypes: Myotonia, MYOTONIC DYSTROPHY 2 (DM2); Mode of inheritance: Other - please specifiy in evaluation comments
Paroxysmal central nervous system disorders v0.21 CNBP Rebecca Foulger Source Wessex and West Midlands GLH was added to CNBP.
Paroxysmal central nervous system disorders v0.3 CNBP Ellen McDonagh Added phenotypes Myotonia; MYOTONIC DYSTROPHY 2 (DM2) for gene: CNBP
Paroxysmal central nervous system disorders v0.2 CNBP Ellen McDonagh gene: CNBP was added
gene: CNBP was added to Paroxysmal neurological disorders, pain disorders and sleep disorders. Sources: Expert Review Red
Mode of inheritance for gene: CNBP was set to Other - please specifiy in evaluation comments
Phenotypes for gene: CNBP were set to Myotonia; MYOTONIC DYSTROPHY 2 (DM2)