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Mitochondrial disorders v9.6 COX4I1 Achchuthan Shanmugasundram Phenotypes for gene: COX4I1 were changed from Mitochondrial complex IV deficiency, nuclear type 16, OMIM:619060 to Mitochondrial complex IV deficiency, nuclear type 16, OMIM:619060
Mitochondrial disorders v9.5 COX4I1 Achchuthan Shanmugasundram Phenotypes for gene: COX4I1 were changed from No OMIM phenotype; Mitochondrial Diseases to Mitochondrial complex IV deficiency, nuclear type 16, OMIM:619060
Mitochondrial disorders v9.5 COX4I1 Achchuthan Shanmugasundram Publications for gene: COX4I1 were set to
Mitochondrial disorders v9.4 COX4I1 Achchuthan Shanmugasundram Classified gene: COX4I1 as Amber List (moderate evidence)
Mitochondrial disorders v9.4 COX4I1 Achchuthan Shanmugasundram Added comment: Comment on list classification: As there are two unrelated cases and functional evidence available in support of the association, this gene can be promoted to green rating in the next GMS update.
Mitochondrial disorders v9.4 COX4I1 Achchuthan Shanmugasundram Gene: cox4i1 has been classified as Amber List (Moderate Evidence).
Mitochondrial disorders v9.3 COX4I1 Achchuthan Shanmugasundram Tag Q2_25_ promote_green tag was added to gene: COX4I1.
Mitochondrial disorders v9.3 COX4I1 Achchuthan Shanmugasundram reviewed gene: COX4I1: Rating: GREEN; Mode of pathogenicity: None; Publications: 28766551, 31290619, 33578848; Phenotypes: Mitochondrial complex IV deficiency, nuclear type 16, OMIM:619060; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Mitochondrial disorders v1.458 COX4I1 Sarah Leigh Mode of inheritance for gene: COX4I1 was changed from to BIALLELIC, autosomal or pseudoautosomal