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Monogenic hearing loss v4.79 DHRSX Achchuthan Shanmugasundram Added comment: Comment on phenotypes: This gene has now been associated with relevant phenotypes in OMIM (MIM #301133).
Monogenic hearing loss v4.79 DHRSX Achchuthan Shanmugasundram Phenotypes for gene: DHRSX were changed from congenital disorder of glycosylation, MONDO:0015286; hearing loss disorder, MONDO:0005365 to Congenital disorder of glycosylation, type 1DD, OMIM:301133
Monogenic hearing loss v4.78 DHRSX Achchuthan Shanmugasundram Tag gene-checked tag was added to gene: DHRSX.
Monogenic hearing loss v4.54 DHRSX Achchuthan Shanmugasundram Phenotypes for gene: DHRSX were changed from congenital disorder of glycosylation, MONDO:0015286; hearing loss disorder, MONDO:0005365 to congenital disorder of glycosylation, MONDO:0015286; hearing loss disorder, MONDO:0005365
Monogenic hearing loss v4.53 DHRSX Achchuthan Shanmugasundram Phenotypes for gene: DHRSX were changed from to congenital disorder of glycosylation, MONDO:0015286; hearing loss disorder, MONDO:0005365
Monogenic hearing loss v4.52 DHRSX Achchuthan Shanmugasundram Tag Q3_24_promote_green was removed from gene: DHRSX.
Monogenic hearing loss v4.52 DHRSX Achchuthan Shanmugasundram changed review comment from: Comment on list classification: There are three unrelated families reported with intellectual disability and hence there is sufficient evidence available for the promotion of this gene to green rating in the next GMS update.; to: Comment on list classification: There are two unrelated families reported with sensorineural hearing loss and hence this gene should be rated amber with current evidence.
Monogenic hearing loss v4.52 DHRSX Achchuthan Shanmugasundram edited their review of gene: DHRSX: Changed rating: AMBER; Changed phenotypes to: congenital disorder of glycosylation, MONDO:0015286, hearing loss disorder, MONDO:0005365
Monogenic hearing loss v4.52 DHRSX Achchuthan Shanmugasundram Entity copied from Intellectual disability v7.60
Monogenic hearing loss v4.52 DHRSX Achchuthan Shanmugasundram gene: DHRSX was added
gene: DHRSX was added to Monogenic hearing loss. Sources: Expert Review Amber
Q3_24_promote_green, Pseudoautosomal region 1 tags were added to gene: DHRSX.
Mode of inheritance for gene: DHRSX was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: DHRSX were set to 38821050
Penetrance for gene: DHRSX were set to Complete