Activity
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15 actions
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| Inherited phaeochromocytoma and paraganglioma excluding NF1 v2.8 | DLST |
Achchuthan Shanmugasundram Tag Q4_23_demote_red was removed from gene: DLST. Tag Q4_23_NHS_review was removed from gene: DLST. Tag Q4_23_expert_review was removed from gene: DLST. Tag curated_removed tag was added to gene: DLST. |
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| Inherited phaeochromocytoma and paraganglioma excluding NF1 v2.8 | DLST | Achchuthan Shanmugasundram changed review comment from: The rating of this gene has been updated togreyfollowing NHS Genomic Medicine Service approval.; to: The rating of this gene has been updated to grey following NHS Genomic Medicine Service approval. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Inherited phaeochromocytoma and paraganglioma excluding NF1 v2.8 | DLST | Achchuthan Shanmugasundram commented on gene: DLST | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Inherited phaeochromocytoma and paraganglioma excluding NF1 v2.7 | DLST |
Achchuthan Shanmugasundram Source Expert Review Removed was added to DLST. Rating Changed from Green List (high evidence) to No List (delete) |
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| Inherited phaeochromocytoma and paraganglioma excluding NF1 v2.6 | DLST | Ivone Leong Tag Q4_23_demote_red tag was added to gene: DLST. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Inherited phaeochromocytoma and paraganglioma excluding NF1 v2.6 | DLST | Ivone Leong commented on gene: DLST: This gene has been tagged for additional expert review due to conflicting reviews. The gene rating will remain Green pending the results of the expert review. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Inherited phaeochromocytoma and paraganglioma excluding NF1 v2.6 | DLST |
Ivone Leong Tag Q4_23_NHS_review tag was added to gene: DLST. Tag Q4_23_expert_review tag was added to gene: DLST. |
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| Inherited phaeochromocytoma and paraganglioma excluding NF1 v2.6 | DLST | Ivone Leong Phenotypes for gene: DLST were changed from Paragangliomas 7, OMIM:618475 to Paragangliomas 7, OMIM:618475; Paragangliomas 7, MONDO:0032771 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Inherited phaeochromocytoma and paraganglioma excluding NF1 v2.2 | DLST | Terri McVeigh reviewed gene: DLST: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Inherited phaeochromocytoma and paraganglioma excluding NF1 v1.21 | DLST | Ivone Leong Tag for-review was removed from gene: DLST. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Inherited phaeochromocytoma and paraganglioma excluding NF1 v1.21 | DLST | Ivone Leong commented on gene: DLST: The rating of this gene has been updated following NHS Genomic Medicine Service approval. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Inherited phaeochromocytoma and paraganglioma excluding NF1 v1.20 | DLST |
Ivone Leong Source Expert Review Green was added to DLST. Rating Changed from Amber List (moderate evidence) to Green List (high evidence) |
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| Inherited phaeochromocytoma and paraganglioma excluding NF1 v1.11 | DLST | Ivone Leong Classified gene: DLST as Amber List (moderate evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Inherited phaeochromocytoma and paraganglioma excluding NF1 v1.11 | DLST | Ivone Leong Gene: dlst has been classified as Amber List (Moderate Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Inherited phaeochromocytoma and paraganglioma excluding NF1 v1.10 | DLST |
Ivone Leong gene: DLST was added gene: DLST was added to Inherited phaeochromocytoma and paraganglioma excluding NF1. Sources: Expert Review for-review tags were added to gene: DLST. Mode of inheritance for gene: DLST was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Publications for gene: DLST were set to 30929736; 33180916 Phenotypes for gene: DLST were set to Paragangliomas 7, OMIM:618475 Review for gene: DLST was set to GREEN Added comment: This gene is associated with a relevant phenotype in OMIM but not in Gene2Phenotype. There is enough evidence to support a gene-disease association. Therefore, this gene should be rated Green at the next review. This gene was suggested to be added and given a Green rating by Ruth Casey (Cambridge University Hospital). Sources: Expert Review Sources: Expert Review |
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