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Intellectual disability v9.330 FICD Ida Ertmanska Tag gene-checked was removed from gene: FICD.
Intellectual disability v9.330 FICD Ida Ertmanska Tag gene-checked tag was added to gene: FICD.
Intellectual disability v9.127 FICD Arina Puzriakova changed review comment from: Paper by Perera et al 2022 has now been published (PMID: 36704923).

An additional 6 unrelated families have been reported with biallelic variants in this gene presenting with motor neuron disease. Unlike the cases reported by Perera et al, these individuals did not display any significant cognitive deficits (PMID: 36136088; 40062579); to: Paper by Perera et al 2022 has now been published (PMID: 36704923).

An additional 6 unrelated families have been reported with biallelic variants in this gene presenting with motor neuron disease. Unlike the cases reported by Perera et al, these individuals did not display any significant cognitive deficits (PMID: 36136088; 40062579). Therefore maintaining the Amber rating on this panel.
Intellectual disability v9.127 FICD Arina Puzriakova commented on gene: FICD
Intellectual disability v9.127 FICD Arina Puzriakova Publications for gene: FICD were set to
Intellectual disability v3.1727 FICD Eleanor Williams Entity copied from Diabetes - neonatal onset v2.53
Intellectual disability v3.1727 FICD Eleanor Williams gene: FICD was added
gene: FICD was added to Intellectual disability. Sources: Expert review,Expert Review Amber
watchlist tags were added to gene: FICD.
Mode of inheritance for gene: FICD was set to BIALLELIC, autosomal or pseudoautosomal
Phenotypes for gene: FICD were set to Neonatal diabetes; Neonatal insulin-dependent diabetes mellitus, HP:0000857; severe neurodevelopmental delay, HP:0012758; skeletal abnormalities.