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Hereditary neuropathy or pain disorder v8.33 FOLR1 Alexander Rossor gene: FOLR1 was added
gene: FOLR1 was added to Hereditary neuropathy or pain disorder. Sources: Expert list
Mode of inheritance for gene: FOLR1 was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: FOLR1 were set to 27743887
Phenotypes for gene: FOLR1 were set to Developmental regression; epilepsy; leukodystrophy; cerebellar atrophy; axonal neuropathy
Review for gene: FOLR1 was set to AMBER
Added comment: Once case associated with neuropathy. A likely cause of neuropathy as multiple other cerebral folate gene variants also causing neuropathy as part of extended phenotype. Certainly not green at this stage but no good evidence it isn't pathogenic so should not be downgraded to red
Sources: Expert list