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Date	Panel	Item	Activity
Filter activities 6 actions
09 Sep 2021	Ocular coloboma v1.44	FOXE3	Eleanor Williams Added comment: Comment on mode of inheritance: Review of mode of inheritance - two reports of coloboma in monoallelic cases from one publication but leaving inheritance as biallelic for now until a 3rd case is reported (PMID: 19708017 - Iseri et al 2009 - identified 2 pedigrees with dominant mutations in the FOXE3 gene by screening a large cohort of 236 anophthalmia-microphthalmia subjects; one with anterior segment anomalies, including Peters’ anomaly, early onset cataract, and coloboma, and another with microphthalmia, coloboma, and cerulean type (blue dot) cataracts.).
09 Sep 2021	Ocular coloboma v1.44	FOXE3	Eleanor Williams Mode of inheritance for gene: FOXE3 was changed from BIALLELIC, autosomal or pseudoautosomal to BIALLELIC, autosomal or pseudoautosomal
16 Nov 2016	Ocular coloboma	FOXE3	Alice Gardham classified FOXE3 as green
16 Nov 2016	Ocular coloboma	FOXE3	Alice Gardham marked FOXE3 as ready
16 Nov 2016	Ocular coloboma	FOXE3	Alice Gardham added FOXE3 to panel
16 Nov 2016	Ocular coloboma	FOXE3	Alice Gardham reviewed FOXE3