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Rare syndromic craniosynostosis or isolated multisuture synostosis v4.127 FTO Achchuthan Shanmugasundram gene: FTO was added
gene: FTO was added to Rare syndromic craniosynostosis or isolated multisuture synostosis. Sources: Literature
Mode of inheritance for gene: FTO was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: FTO were set to 26697951; 36980886
Phenotypes for gene: FTO were set to craniosynostosis, MONDO:0015469
Review for gene: FTO was set to RED
Added comment: A homozygous variant in FTO (c.956G>A; p.Arg322Gln) was described in one individual with multiple malformation syndrome, which included craniosynostosis. Craniosynostosis is not a consistent feature of variants in FTO (PMID:26697951).
Sources: Literature