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Fetal hydrops v1.86 GATA1 Sarah Leigh Phenotypes for gene: GATA1 were changed from Anaemia, X-linked, with/without neutropaenia and/or platelet abnormalities, MIM#300835 to Anaemia, X-linked, with/without neutropaenia and/or platelet abnormalities, OMIM:300835; Hemolytic anemia due to elevated adenosine deaminase, OMIM:301083
Fetal hydrops v1.85 GATA1 Sarah Leigh Publications for gene: GATA1 were set to 10700180; 33082562
Fetal hydrops v1.84 GATA1 Sarah Leigh Classified gene: GATA1 as Green List (high evidence)
Fetal hydrops v1.84 GATA1 Sarah Leigh Gene: gata1 has been classified as Green List (High Evidence).
Fetal hydrops v1.83 GATA1 Sarah Leigh reviewed gene: GATA1: Rating: GREEN; Mode of pathogenicity: None; Publications: 20301538, 30914438, 29949202, 35580337; Phenotypes: Hemolytic anemia due to elevated adenosine deaminase, OMIM:301083; Mode of inheritance: None
Fetal hydrops v1.83 GATA1 Sarah Leigh Publications for gene: GATA1 were set to 10700180
Fetal hydrops v1.64 GATA1 Irina Adamena reviewed gene: GATA1: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 33082562; Phenotypes: Nonimmune hydrops fetalis; Mode of inheritance: X-LINKED: hemizygous mutation in males, biallelic mutations in females
Fetal hydrops v1.16 GATA1 Zornitza Stark gene: GATA1 was added
gene: GATA1 was added to Fetal hydrops. Sources: Expert list
Mode of inheritance for gene: GATA1 was set to X-LINKED: hemizygous mutation in males, biallelic mutations in females
Publications for gene: GATA1 were set to 10700180
Phenotypes for gene: GATA1 were set to Anaemia, X-linked, with/without neutropaenia and/or platelet abnormalities, MIM#300835
Review for gene: GATA1 was set to GREEN
gene: GATA1 was marked as current diagnostic
Added comment: Can present with severe hydrops in utero requiring transfusion.
Sources: Expert list