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DDG2P v6.177 GDF3 Achchuthan Shanmugasundram Mode of pathogenicity for gene: GDF3 was changed from Other to None
DDG2P v6.17 GDF3 Achchuthan Shanmugasundram edited their review of gene: GDF3: Added comment: The DDG2P confidence category, allelic requirement and molecular mechanism for GDF3-related multiple malformations are limited, monoallelic_autosomal and undetermined (PMIDs: 19864492, 29260090). More details can be found in https://www.ebi.ac.uk/gene2phenotype/lgd/G2P00932.; Changed publications to: 29260090, 19864492; Changed phenotypes to: GDF3-related multiple malformations, GDF3 multiple malformations, OMIM:613702, OMIM:613702.0, MONDO:0013375
DDG2P v3.12 GDF3 Achchuthan Shanmugasundram reviewed gene: GDF3: Rating: RED; Mode of pathogenicity: Other; Publications: 19864492, 29260090; Phenotypes: GDF3 multiple malformations, OMIM:613702; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
DDG2P v3.11 GDF3 Achchuthan Shanmugasundram Mode of pathogenicity for gene GDF3 was changed from Other - please provide details in the comments to Other
Publications for gene: GDF3 were updated from to 19864492; 29260090
DDG2P v0.2 GDF3 Rebecca Foulger reviewed gene: GDF3: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
DDG2P v0.1 GDF3 Rebecca Foulger Added phenotypes MICROPHTHALMIA ISOLATED WITH COLOBOMA TYPE 6 613703 for gene: GDF3
DDG2P v0.1 GDF3 Rebecca Foulger Added phenotypes KLIPPEL-FEIL SYNDROME TYPE 3 613702 for gene: GDF3
DDG2P v0.1 GDF3 Rebecca Foulger gene: GDF3 was added
gene: GDF3 was added to DDG2P. Sources: Expert Review Red,DD-Gene2Phenotype
Mode of inheritance for gene: GDF3 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes for gene: GDF3 were set to MICROPHTHALMIA ISOLATED TYPE 7 613704
Mode of pathogenicity for gene: GDF3 was set to Other - please provide details in the comments