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Monogenic short stature v1.27 GH1 Ida Ertmanska reviewed gene: GH1: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Monogenic short stature v1.26 GH1 Ida Ertmanska Tag Q1_25_ NHS_review was removed from gene: GH1.
Tag Q1_25_ promote_green was removed from gene: GH1.
Monogenic short stature v1.26 GH1 Ida Ertmanska reviewed gene: GH1: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Monogenic short stature v1.25 GH1 Ida Ertmanska Source Expert Review Green was added to GH1.
Source NHS GMS was added to GH1.
Rating Changed from Amber List (moderate evidence) to Green List (high evidence)
Monogenic short stature v1.15 GH1 Sarah Leigh reviewed gene: GH1: Rating: GREEN; Mode of pathogenicity: None; Publications: 8496314, 8288694, 8552145, 10689634, 18554279, 17726075; Phenotypes: ; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Monogenic short stature v1.15 GH1 Sarah Leigh Tag Q1_25_ NHS_review tag was added to gene: GH1.
Tag Q1_25_ promote_green tag was added to gene: GH1.
Monogenic short stature v1.15 GH1 Sarah Leigh Classified gene: GH1 as Amber List (moderate evidence)
Monogenic short stature v1.15 GH1 Sarah Leigh Gene: gh1 has been classified as Amber List (Moderate Evidence).
Monogenic short stature v1.14 GH1 Sarah Leigh Phenotypes for gene: GH1 were changed from Growth hormone deficiency to Growth hormone deficiency, isolated, type IA, OMIM:262400; Growth hormone deficiency, isolated, type IB, OMIM:612781; Growth hormone deficiency, isolated, type II, OMIM:173100; Growth hormone deficiency; Kowarski syndrome, OMIM:262650
Monogenic short stature v1.1 GH1 Melissa Connolly reviewed gene: GH1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Growth hormone deficiency, Kowarski syndrome; Mode of inheritance: BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Monogenic short stature v1.1 GH1 Adam Gunning reviewed gene: GH1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Growth hormone deficiency; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Monogenic short stature v0.108 GH1 Arina Puzriakova Entity copied from Growth failure in early childhood v3.78
Monogenic short stature v0.108 GH1 Arina Puzriakova gene: GH1 was added
gene: GH1 was added to Monogenic short stature. Sources: Expert Review Red
Mode of inheritance for gene: GH1 was set to BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Phenotypes for gene: GH1 were set to Growth hormone deficiency