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Paediatric disorders - additional genes v6.18 IGFALS Sarah Leigh Tag Q2_25_ promote_green tag was added to gene: IGFALS.
Tag Q2_25_ NHS_review tag was added to gene: IGFALS.
Paediatric disorders - additional genes v6.18 IGFALS Sarah Leigh reviewed gene: IGFALS: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Paediatric disorders - additional genes v6.18 IGFALS Sarah Leigh Publications for gene: IGFALS were set to
Paediatric disorders - additional genes v6.17 IGFALS Sarah Leigh Phenotypes for gene: IGFALS were changed from short stature to Acid-labile subunit, deficiency of, OMIM:615961; short stature due to primary acid-labile subunit deficiency, MONDO:0014420
Paediatric disorders - additional genes v6.16 IGFALS Sarah Leigh Classified gene: IGFALS as Amber List (moderate evidence)
Paediatric disorders - additional genes v6.16 IGFALS Sarah Leigh Gene: igfals has been classified as Amber List (Moderate Evidence).
Paediatric disorders - additional genes v6.3 IGFALS Tracy Lester gene: IGFALS was added
gene: IGFALS was added to Paediatric disorders - additional genes. Sources: NHS GMS
Mode of inheritance for gene: IGFALS was set to BIALLELIC, autosomal or pseudoautosomal
Phenotypes for gene: IGFALS were set to short stature
Penetrance for gene: IGFALS were set to unknown
Review for gene: IGFALS was set to GREEN
gene: IGFALS was marked as current diagnostic
Added comment: This gene is on the R453 panel but absent from R27 - adding so that syndromic cases of short stature have all genes on the R453 panel covered.
Sources: NHS GMS