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Intellectual disability v7.27 IPO8 Sarah Leigh reviewed gene: IPO8: Rating: AMBER; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None
Intellectual disability v7.27 IPO8 Sarah Leigh Publications for gene: IPO8 were set to 34010604; 34010605
Intellectual disability v7.26 IPO8 Sarah Leigh Phenotypes for gene: IPO8 were changed from Intellectual disability to VISS syndrome, OMIM:619472; VISS syndrome, MONDO:0859177
Intellectual disability v7.25 IPO8 Sarah Leigh Publications for gene: IPO8 were set to PMID 34010604; 34010605
Intellectual disability v7.24 IPO8 Sarah Leigh Classified gene: IPO8 as Amber List (moderate evidence)
Intellectual disability v7.24 IPO8 Sarah Leigh Gene: ipo8 has been classified as Amber List (Moderate Evidence).
Intellectual disability v7.22 IPO8 Nour Elkhateeb changed review comment from: Intellectual disability is reported in some affected individuals with IPO8-related VISS syndrome (PMID 34010604, 34010605).
Sources: Literature; to: Intellectual disability is reported in some affected individuals with IPO8-related VISS syndrome (PMID 34010604, 34010605).
Sources: Literature
Intellectual disability v7.22 IPO8 Nour Elkhateeb gene: IPO8 was added
gene: IPO8 was added to Intellectual disability. Sources: Literature
Mode of inheritance for gene: IPO8 was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: IPO8 were set to PMID 34010604; 34010605
Phenotypes for gene: IPO8 were set to Intellectual disability
Penetrance for gene: IPO8 were set to unknown
Added comment: Intellectual disability is reported in some affected individuals with IPO8-related VISS syndrome (PMID 34010604, 34010605).
Sources: Literature