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Hereditary ataxia v1.343 ISCA-37404-Loss Arina Puzriakova Tag curated_removed tag was added to Region: ISCA-37404-Loss.
Hereditary ataxia v1.343 ISCA-37404-Loss Arina Puzriakova Classified Region: ISCA-37404-Loss as No list
Hereditary ataxia v1.343 ISCA-37404-Loss Arina Puzriakova Added comment: Comment on list classification: Removing this region as it has been deprecated by ClinGen and has been subsumed into ISCA-37478 which is green on multiple GMS panels (https://panelapp.genomicsengland.co.uk/panels/entities/ISCA-37478-Loss)
Hereditary ataxia v1.343 ISCA-37404-Loss Arina Puzriakova Region: isca-37404-loss has been removed from the panel.
Hereditary ataxia v1.299 ISCA-37404-Loss Arina Puzriakova commented on Region: ISCA-37404-Loss
Hereditary ataxia v1.299 ISCA-37404-Loss Arina Puzriakova GRCh38 position for ISCA-37404-Loss was changed from 22782170-28134729 to 22782170-28134728.
Required Overlap Percentage for ISCA-37404-Loss was changed from 80 to 60.
Hereditary ataxia v1.122 ISCA-37404-Loss Louise Daugherty Region: ISCA-37404-Loss was added
Region: ISCA-37404-Loss was added to Hereditary ataxia. Sources: ClinGen,Expert Review Green
Mode of inheritance for Region: ISCA-37404-Loss was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Publications for Region: ISCA-37404-Loss were set to 22045295; 7611294
Phenotypes for Region: ISCA-37404-Loss were set to microcephaly; Developmental delay, muscle weakness; Mental retardation; Angelman syndrome; 176270; Prader-Willi syndrome; 105831