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Hereditary spastic paraplegia v1.247 KIF1C Arina Puzriakova changed review comment from: Comment on list classification: Upgraded from Amber to Green as there are now sufficient unrelated cases (>3) of spasticity associated with variants in this gene (updated references in publications list). KDM5C is also already Green on the GMS-equivalent HSP panels.; to: Comment on list classification: Upgraded from Amber to Green as there are now sufficient unrelated cases (>3) of spasticity associated with variants in this gene (updated references in publications list). KIF1C is also already Green on the GMS-equivalent HSP panels.
Hereditary spastic paraplegia v1.245 KIF1C Arina Puzriakova Classified gene: KIF1C as Green List (high evidence)
Hereditary spastic paraplegia v1.245 KIF1C Arina Puzriakova Added comment: Comment on list classification: Upgraded from Amber to Green as there are now sufficient unrelated cases (>3) of spasticity associated with variants in this gene (updated references in publications list). KDM5C is also already Green on the GMS-equivalent HSP panels.
Hereditary spastic paraplegia v1.245 KIF1C Arina Puzriakova Gene: kif1c has been classified as Green List (High Evidence).
Hereditary spastic paraplegia v1.244 KIF1C Arina Puzriakova Tag watchlist was removed from gene: KIF1C.
Hereditary spastic paraplegia v1.244 KIF1C Arina Puzriakova Publications for gene: KIF1C were set to 24482476; 24319291; 24482476; 17273843
Hereditary spastic paraplegia v1.243 KIF1C Arina Puzriakova Phenotypes for gene: KIF1C were changed from Spastic ataxia 2,autosomal recessive to Spastic ataxia 2, autosomal recessive, OMIM:611302
Hereditary spastic paraplegia v1.203 KIF1C Louise Daugherty reviewed gene: KIF1C: Rating: AMBER; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None
Hereditary spastic paraplegia v1.199 KIF1C Louise Daugherty Classified gene: KIF1C as Amber List (moderate evidence)
Hereditary spastic paraplegia v1.199 KIF1C Louise Daugherty Gene: kif1c has been classified as Amber List (Moderate Evidence).
Hereditary spastic paraplegia v1.114 KIF1C Sarah Leigh Publications for gene: KIF1C were set to Dor et al. (2014)
Hereditary spastic paraplegia v1.71 KIF1C Chris Buxton reviewed gene: KIF1C: Rating: AMBER; Mode of pathogenicity: None; Publications: 24482476, 24319291, 24482476, 17273843; Phenotypes: cerebellar ataxia, dysarthria, variable spasticity of the lower limbs, Cognition is not affected; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Hereditary spastic paraplegia KIF1C Alice Gardham reviewed KIF1C