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Proteinuric renal disease v2.41 KIRREL1 Eleanor Williams Classified gene: KIRREL1 as Amber List (moderate evidence)
Proteinuric renal disease v2.41 KIRREL1 Eleanor Williams Added comment: Comment on list classification: Promoting this gene from grey to amber. 2 cases plus some limited functional data.
Proteinuric renal disease v2.41 KIRREL1 Eleanor Williams Gene: kirrel1 has been classified as Amber List (Moderate Evidence).
Proteinuric renal disease v2.40 KIRREL1 Eleanor Williams Phenotypes for gene: KIRREL1 were changed from Steroid-resistant nephrotic syndrome to steroid-resistant nephrotic syndrome MONDO:0044765
Proteinuric renal disease v2.39 KIRREL1 Eleanor Williams reviewed gene: KIRREL1: Rating: AMBER; Mode of pathogenicity: None; Publications: 31472902; Phenotypes: steroid-resistant nephrotic syndrome MONDO:0044765; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Proteinuric renal disease v2.33 KIRREL1 Zornitza Stark gene: KIRREL1 was added
gene: KIRREL1 was added to Proteinuric renal disease. Sources: Literature
Mode of inheritance for gene: KIRREL1 was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: KIRREL1 were set to 31472902
Phenotypes for gene: KIRREL1 were set to Steroid-resistant nephrotic syndrome
Review for gene: KIRREL1 was set to AMBER
Added comment: Two unrelated families reported with bi-allelic variants and limited functional data.
Sources: Literature